Phys 3

Question 1

Three physical factors that contribute to GFR

Answer 1

1. Hydraulic conductivity (who hole it is)
2. Surface area for filtration
3. Capillary ultrafiltration pressure (PUF)

1 X 2 = Kf

Question 2

What determines Pgc?

Answer 2

1. Renal arterial blood
2. Afferent arteriolar resistance
3. Efferent arteriolar resistance

Question 3

AA constriction causes? dilation?

Answer 3

1. decreased GFR, Pgc, RBF (ACE inhibitors)

2. increased GFR, Pgc, RBF (Prostaglandins, NO, Bradykinin, Dopamine, ANP)

Question 4

EA constriction causes? dilation?

Answer 4

1. increased GFR, Pgc, decreased RBF (Angiotensin II)

2. decreased GFR, Pgc, increased RBF (Sympathetics)

Question 5

Three physiological determinants of GFR and RBF

Answer 5

1. sympathetics
2. hormones
3. vasoactive signals