PHYPHARM QUIZ 1 Flashcards
considered to be a bounded space or an exact quantity of material
System
consists of at least two phases with one or more dispersed (internal) phases contained in a single continuous (external) phase.
Dispersion
defined as a distinct homogeneous part of a system separated by definite boundaries from other parts of the system
Phase
Material substances can be mixed together to form a variety of pharmaceutical mixtures (or dispersions) such as?
true solutions, colloidal dispersion and coarse dispersion
A mixture of two or more components that forms a homogeneous molecular dispersion
True solution
A one-phase system
True solution
The dispersed phase completely dissolves, cannot scatter light, and cannot be visualized using microscopy
True solution
Represents a system having a particle size intermediate between that of a true solution and a coarse dispersion, roughly between 1 to 500 nm.
Colloidal Dispersion
What are the examples of colloidal Dispersion?
blood, liposomes, and zinc oxide paste.
A system having a particle size greater than ~ 500 nm (0.5 um)
Coarse dispersion
Two common pharmaceutical coarse dispersions are?
emulsions(liquid-liquid) and suspension (solid-liquid)
aka molecular dispersions?
True solution
composed of two substances is known as a binary solution, and the components are referred to as the solvent and solute.
True solutions
The physical properties of substances can be classified as?
Colligative
Additive
Constitutive
Depend mainly on the number of particles in a solution.
Colligative
What are the examples of colligative?
Osmotic pressure, Vapor pressure lowering, Freezing point depression, and Boiling point elevation
Depends on the total contribution of atoms in the molecule or on the sum of the properties of the constituents in a solution
Additive
What are the examples of Additive?
Molecular Weight
Depends on the arrangement and to a lesser extent on the number and kind of atoms within a molecule.
Constitutive
Give the examples of Constitutive
Refractive index, Optical rotation
In the field of thermodynamics, physical properties of systems are classified as
Extensive
Intensive
which depends on the quantity of matter in the system
Extensive
Give the example of Extensive?
mass and volume
which are independent of the amount of substances in the system
Intensive
Give the example of intensive?
temperature, pressure, density, surface tension and viscosity of a pure liquid.
is defined as a chemically and physically homogeneous mixture of two or more substances.
Solution
is a mixture of only two components. These 2 components are called the solute and solvent.
Binary solution
Gas Gas
Air
Liquid Gas
Water in oxygen
Solid Gas
Iodine vapor in air
Gas Liquid
Carbonated Water
Liquid Liquid
Alcohol in water
Solid Liquid
Aqueous sodium chloride solution
Gas Solid
Hydrogen palladium
Liquid Solid
Mineral oil in paraffin
Solid Solid
Gold- silver mixture, mixture of alums
Solutes are mainly divided into two?
electrolytes and non electrolytes
are substances that do not ionize when dissolved in water and therefore do not conduct an electric current through the solution.
Non electrolyte
What are the examples of non electrolyte?
sucrose, glycerin, naphthalene and urea
are substances that form ions in solution, conduct electric current, and show apparent “anomalous” colligative properties than nonelectrolytes.
Electrolyte
What are the examples of electrolyte?
HCl & sodium sulfate (strong electrolytes) and ephedrine & phenobarbital (weak electrolytes).
Greek name of colligative properties?
“collected together”
What are the four colligative properties?
Vapor pressure lowering
Boiling point elevation
Freezing point depression
Osmotic pressure