MICROBIO LAB QUIZ 2 Flashcards

1
Q

What are the Drugs used for nematodes?

A

Albendazole
Ivermectin
Diethylcarbamazine
Mebendazole
Pyrantel Pamoate

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2
Q

What is the MOA of Albendazole?

A

inhibits microbial assembly

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3
Q

What is the MOA of Ivermectin

A

Immobilized Gaba leading to Paralysis

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4
Q

What is the MOA of Diethylcarbamazine

A

immobilizes microfilariae by unknown mechanism

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5
Q

What is the MOA of Mebendazole?

A

inhibits microtubule assembly and Glucose uptake

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6
Q

What is the MOA of Pyrantel Pamoate

A

Stimulates nicotinic receptors leading to paralysis

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7
Q

What is the Microorganisms associated with Albendazole?

A

Ascariasis Lumbricoides
Necator Americanus (New world Hookworm)
Trichuris trichuria (Whip worm)
Enterobius vermicularis (Pinworm, seat worm)

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8
Q

What disease is used for albendazole?

A

Ascariasis
Hookworm infection
Trichuriasis
Enterobiasis

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9
Q

What diseases is used for Ivermectin?

A

African River Disease

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10
Q

What is the microorganisms associated with Ivermectin?

A

Onchocerca volvulus

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11
Q

What is the microorganisms associated with Diethylcarbamazine?

A

Wuchereria bancrofti (scrotal lymphatic)
Brugia malayi (limb lymphatic)
Loaloa (African eye worm)

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12
Q

What diseases is used for DEC?

A

Lymphatic filariasis
Loaloasis

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13
Q

What is the microorganisms used for mebendazole?

A

Ascaris lumbricoides
Trichuris trichuria (Whipworm)
Enterobius vermicularis (pinworm, seat worm)

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14
Q

What is diseases is used for mebendazole?

A

Ascariasis
Trichuriasis
Enterobiasis

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15
Q

What are the microorganisms associated of pyrantel Pamoate

A

Trichuris trichuria (Whipworm)
Enterobius Vermicularis (pinworm, seat worm)

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16
Q

What is are the diseases used for pyrantel pamoate?

A

Trichuriasis
Enterobiasis

17
Q

What are the drug used against cestodes?

A

Praziquantel

18
Q

What is the MOA of praziquantel

A

Uncertain
Generation of ROS
Promotes Ca2+influx leading to paralysis

19
Q

What is the famous MOA of praziquantel?

A

Inhibits adenosine influx

20
Q

What are the microorganisms associated with praziquantel?

A

S.japonicum
S.haematobium
S.mansoni
Paragonimus westermani
Clonorchis sinensis
Taenia solium
Taenia saginata
Diphyllobothrium latum (broad worms, long intestinal tapeworm)

21
Q

What are the diseases used for Praziquantel?

A

Shistomiasis
Clonorchis
Paragonimiasis
Taeniasis
Diphyllobothriasis

22
Q

What are the Drugs used against cestodes?

A

Albendazole
Niclosamide
Praziquantel

23
Q

What is the MOA of Albendazole?

A

inhibition of microtubule assembly

24
Q

What are the microorganisms associated in albendazole in cestodes?

A

Taenia saginata
Taenia solium

25
What are the diseases used in albendazole in cestodeS?
Taeniasis (Neurocystosis)
26
What is the MOA of Niclosamide?
Activating ATPase
27
What are the microorganisms associated in Niclosamide?
none
28
What are the diseases used in niclosamide?
Alternatize drug for praziquantel (beef, pork, fish tapeworm)
29
What is the MOA of praziquantel?
Uncertain Generation of ROS Promotes Ca2+influx leading to paralysisW
30
What are the microorganisms associated with praziquantel in cestodes?
Taenia saginata (Beef) Taenia solium (Pork) Diphyllobothrium latum (Broad worm, Long intestinal tapeworm)
31
What are the diseases used in praziquantel in cestodes?
Taeniasis Diphyllobothriasis
32