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Flashcards for Midterms > MICROBIO LAB QUIZ 2 > Flashcards

MICROBIO LAB QUIZ 2 Flashcards

1
Q

What are the Drugs used for nematodes?

A

Albendazole
Ivermectin
Diethylcarbamazine
Mebendazole
Pyrantel Pamoate

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2
Q

What is the MOA of Albendazole?

A

inhibits microbial assembly

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3
Q

What is the MOA of Ivermectin

A

Immobilized Gaba leading to Paralysis

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4
Q

What is the MOA of Diethylcarbamazine

A

immobilizes microfilariae by unknown mechanism

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5
Q

What is the MOA of Mebendazole?

A

inhibits microtubule assembly and Glucose uptake

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6
Q

What is the MOA of Pyrantel Pamoate

A

Stimulates nicotinic receptors leading to paralysis

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7
Q

What is the Microorganisms associated with Albendazole?

A

Ascariasis Lumbricoides
Necator Americanus (New world Hookworm)
Trichuris trichuria (Whip worm)
Enterobius vermicularis (Pinworm, seat worm)

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8
Q

What disease is used for albendazole?

A

Ascariasis
Hookworm infection
Trichuriasis
Enterobiasis

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9
Q

What diseases is used for Ivermectin?

A

African River Disease

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10
Q

What is the microorganisms associated with Ivermectin?

A

Onchocerca volvulus

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11
Q

What is the microorganisms associated with Diethylcarbamazine?

A

Wuchereria bancrofti (scrotal lymphatic)
Brugia malayi (limb lymphatic)
Loaloa (African eye worm)

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12
Q

What diseases is used for DEC?

A

Lymphatic filariasis
Loaloasis

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13
Q

What is the microorganisms used for mebendazole?

A

Ascaris lumbricoides
Trichuris trichuria (Whipworm)
Enterobius vermicularis (pinworm, seat worm)

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14
Q

What is diseases is used for mebendazole?

A

Ascariasis
Trichuriasis
Enterobiasis

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15
Q

What are the microorganisms associated of pyrantel Pamoate

A

Trichuris trichuria (Whipworm)
Enterobius Vermicularis (pinworm, seat worm)

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16
Q

What is are the diseases used for pyrantel pamoate?

A

Trichuriasis
Enterobiasis

17
Q

What are the drug used against cestodes?

A

Praziquantel

18
Q

What is the MOA of praziquantel

A

Uncertain
Generation of ROS
Promotes Ca2+influx leading to paralysis

19
Q

What is the famous MOA of praziquantel?

A

Inhibits adenosine influx

20
Q

What are the microorganisms associated with praziquantel?

A

S.japonicum
S.haematobium
S.mansoni
Paragonimus westermani
Clonorchis sinensis
Taenia solium
Taenia saginata
Diphyllobothrium latum (broad worms, long intestinal tapeworm)

21
Q

What are the diseases used for Praziquantel?

A

Shistomiasis
Clonorchis
Paragonimiasis
Taeniasis
Diphyllobothriasis

22
Q

What are the Drugs used against cestodes?

A

Albendazole
Niclosamide
Praziquantel

23
Q

What is the MOA of Albendazole?

A

inhibition of microtubule assembly

24
Q

What are the microorganisms associated in albendazole in cestodes?

A

Taenia saginata
Taenia solium

25
Q

What are the diseases used in albendazole in cestodeS?

A

Taeniasis (Neurocystosis)

26
Q

What is the MOA of Niclosamide?

A

Activating ATPase

27
Q

What are the microorganisms associated in Niclosamide?

A

none

28
Q

What are the diseases used in niclosamide?

A

Alternatize drug for praziquantel
(beef, pork, fish tapeworm)

29
Q

What is the MOA of praziquantel?

A

Uncertain
Generation of ROS
Promotes Ca2+influx leading to paralysisW

30
Q

What are the microorganisms associated with praziquantel in cestodes?

A

Taenia saginata (Beef)
Taenia solium (Pork)
Diphyllobothrium latum (Broad worm, Long intestinal tapeworm)

31
Q

What are the diseases used in praziquantel in cestodes?

A

Taeniasis
Diphyllobothriasis

32
Q
A

Flashcards for Midterms (11 decks)

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