Phosphorus Flashcards
one of the most important minerals physiologically and biochemically
phosphorous
what % of P is in bone
80% - this is associated with Ca
amount of P in blood
~35-45mg P/100ml
most in red blood cells
what organ plays an important role in the maintenance of P balance?
kidneys
2 main functions of P
1) bone function - 80% of P is in bone
2) remaining 20% is involved in most organic reactions as an enzyme or coenzyme constituent
20% of P is involved in most organic reactions as an enzyme or coenzyme constituent such as:
a. necessary for phosphorylations in CHO metabolism
b. energy transfers -NAD, NADP
c. constituents of ATP
d. constituent nucleoproteins, phosphoproteins, DNA, RNA, phospholipids in cell membrane
active absorption primarily occurs where
in the distal duodenum
P is mainly absorbed as:
free phosphate
5 conditions favoring absorption of P
1) presence of K
2) normal Ca++, Fe++, Mg++ and some trace minerals (if any of these are present in high amts, insoluble salts can be formed which are poorly absorbed)
3) Vit. D is essential for good absorption
4) Acid medium favors good absorption
5) low phytic acid
4 consequences of deficiency
1) decreased growth
2) decreased bone growth
3) rickets or osteomalacia
4) pica
a consequence of phosphorous deficiency that occurs in grazing animals that caused fragile bones, lameness, low fertility. Marked by chewing on bones, wood, or any material animals have access to
Pica
in young confined calves and suckling animals, rickets are usually due to
lack of vit. D
Rickets occurrence in poultry and swine are due to
Ca or Vit. D deficiency
Rickets are due to P deficiency in ___
ruminants
P most important mineral for ruminant besides salt; especially in pregnant animals and in certain range areas
***Principle site in the body where phosphorus would be found
bone
