Phenacetin Recrystallization

Question 1

What is the formula for the synthesis of last week’s product?

Answer 1

Acetaminophen + Bromoethane → Phenacetin

Question 2

What is the structure of acetaminophen?

Answer 2

Benzene, OH opposite to a NH with ketone attached (2 carbons)

Question 3

What is the structure of bromoethane?

Answer 3

CH2CH3Br

Question 4

What is the structure of phenacetin?

Answer 4

Benzene, NH with ketone attached (2 carbons) opposite to OCH2CH3

Question 5

What is the formula for theoretical yield?

Answer 5

Grams Reactant * 1/MM Reactant * Mole Ratio * MM Product

Question 6

What is the formula for percent yield? What about for hot solubility yield?

Answer 6

Actual/Theoretical * 100

mL*(hot sol) - mL(cold sol) over grams times 100

Question 7

What is the formula for percent error?

Answer 7

Expected-Measured over Expected *100

Question 8

What is the purpose of the brine/NaCl?

Answer 8

prevent emulsions and force out H2O

Question 9

What is the purpose of the sodium sulfate (Na2SO4)?

Answer 9

drying agent with high capacity and medium rate, forms sodium sulfate hydrate (a solid) to remove water