Grinard, Part I Flashcards
Structure of benzophenone
carbon connected to two benzene rings and double bonded to oxygen
Structure of bromobenzene
benzene ring connected to Br
Structure of triphenylmethanol
carbon connected to three benzene rings and single bonded to OH
Structure of diethyl ether
oxygen connected on both sides to ethane
Structure of iodine
I2
Structure of hydrochloric acid
HCl
Structure of anhydrous sodium sulfate
Na2SO4
Structure of magnesium metal
mg
Structure of biphenyl
two benzene ring connected to each other
Structure of petroleum ether
c5-c6 hydrocarbon mix
Structure of isopropyl alcohol
carbon connected to OH and two other Cs
Give the balanced equation for the reaction
Bromobenzene + Mg -> Phenylmagnesium bromide
Phenylmagnesium bromide + benzophenone -> triphenylmethanol
Describe the side reaction to form biphenyl
Phenylmagnesium bromide + bromobenzene -> biphenyl and MgBr2
Why does everything have to be dry?
to prevent the reaction of RMgX + HOH -> RH + MgXOH
Give some examples of how the reaction can be initiated
scratching/crushing mg
adding I2 crystal, 1,2-dibromoethane, or PhMgBr
use of ultrasound
heating (limited by BP of ether)
How can the side reaction be minimized?
adding bromobenzene slowly
Give some examples of the hazards of Et2O
Flammable
Hard to dispense (generates pressure), vaporize in exothermic reactions
Need ice water in condenser
Forms explosive peroxides with air, absorbs moisture with air
Anesthetic in high concentrations
How does reaction rate relate to temperature?
reaction rate doubles with every 10*C increase
Name the drying agent we will use (in drying tube)
drierite
How is H2 gas formed?
The HCl added to neutralize the reaction will react with unused Mg metal, producing the H2 gas
