Phase 1 Flashcards
1
Q
Non IHC based Molecular testing
A
FISH
2
Q
Molecular Aberrations are
A
Alterations in Single Genes that regulate cell growth
3
Q
% Molecular Aberrations in GBC - HER2 amplification or overexpression
A
19.1%
4
Q
HER2 amplification/overexpression in eCCA
A
17.4%
5
Q
HER2 amplification/overexpression in iCCA
A
4.8%
6
Q
FGFR2 fusions in iCCA
A
9-15%
7
Q
IDH1 mutations in iCCA
A
10-20%
8
Q
BRAF mutations in iCCA
A
3-7.1%
9
Q
BRAF in eCCA
A
3%
10
Q
BRAF in GBC
A
1-5.9%
11
Q
Testing Options for Biomarkers include
A
IHC, ISH,NGS
12
Q
Testing technique for HER2
A
IHC, ISH, NGS
13
Q
Testing Technique for PD-L1
A
IHC
14
Q
Testing Technique for MSI-H
A
IHC and NGS
15
Q
Testing Technique for NTRK
A
NGS
