Pharna

Question 1

The 4 types of action in drugs, explain and mention examples?

Answer 1

Stimulation: ehancement of a biological response eg adrenaline increase heart rate
Depression: diminution of a biological response eg barbiturates depress CNS
Cytotoxic action: toxic effects to kill cancer cell or invading microorganisms.
Replacement: replacement of the natural hormones or enzymes which are deficient in the body eg insulin.

Question 2

Name the receptors present on cell membrane?

Answer 2

Alpha and beta receptors and muscarinic and nicotinic receptors

Question 3

Receptors inside the cytoplasm?

Answer 3

Steroid hormones and vitamin D because they are lipid soluble and easily enter the cytoplasm

Question 4

Receptors Inside the nucleus?

Answer 4

Thyroid hormones

Question 5

Ability of a drug to bind to a specific receptor forming drug/receptor complex ?

Answer 5

Affinity

Question 6

Efficacy/intrinsic activity?

Answer 6

Ability to evoke a response