Patho Of Penis And Prostate Flashcards
Balanitis and Balanoposthitis
Inflammation on glans penis and prepuce caused by candida which is due local hygiene and uncircumcision
Phimosis
Tightening of the prepuce due to scarring or congenital disorder
Syphilis
Chronic venereal caused by treponema pallidum
Syphilitic chancre
Painless Lesion on penis, well defined and button like appearance
Site Condylomata Lata
Gross ?
Flexures anoregion, upper thigh and axillary
Gross raised plaque with silver erosion
Gumma microscopy and gross
Appear in tertiary syphilis, Affect liver and brain, cause fibrosis
Microscopy central zone necrosis, with fibrosis
HSV clinical manifestation and microscopy
Painful vesicular lesions, neonatal herpes, encephalitis, pneumonitis
Microscopy caused by cowdry bodies
Predisposing factors of neoplasms ?
Smoking, uncircumcised patients, HPV type 16,18
Type of neoplasms ?
Situ carcinoma ( Bowen and Bowenoid)
Invasive squamous cell carcinoma
Solitary plaque on shaft, malignancy without invasion
Bowens disease( situ scc)
Multiply plaque on shaft, never reach invasion
Bowenoid
Where do most lesions happen in which part of prostate and where do most cancers happen ?
Hyperplastic lesions arise from inner transitional zone
While cancers arise from peripheral zone
BPH etiology and pathogenesis
Circulating testosterone is taken by glandular and stromal epithelium of the prostate converted to DHT which become enlarged and cause BPH
Nodular prostatic hyperplasia/ BPH microscopy
Enlarged or profilerating stromal cells, is lined by two layer of cells
And shows “PINK SECRETIONS (corpora amylacae) “
Prostatic carcinoma grossly and microscopy
Gray whitish lesions that start at PERIPHERAL ZONE of prostate
Microscopy -> prominent nucleoli, lacking basal cells, papillary infolding, and single layer of epithelium
