Metaplasia Flashcards

1
Q

Metaplasia ?

A

Change of one type of cell to another of the SAME CLASS

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2
Q

What causes metaplasia

A

Chronic irritation/ infection
Vitamin A deficiency

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3
Q

Types of metaplasia

A

Connective tissue
Mesothelial
Endothelial
Tumor

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4
Q

Give me an example of epithelial metaplasia ?

A

Columnar epithelium into squamous due to chronic cholecystitis due to presence of stone

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5
Q

Transitional epithelium into squamous in ?

A

Urinary bladder due to hilharziasis(parasitic infections)

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6
Q

Pseudostratified columnar to squamous in?

A

Bronchitis due to smoking and infection

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7
Q

Change of type connective tissue to another type of connective tissue?

A

Connective tissue metaplasia

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8
Q

Give me an example of connective tissue metaplasia ?

A

Myositis ossificans which is change of fibrous tissue into bone/cartilage

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9
Q

Disordered cellular proliferation ?

A

Dysplasia

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10
Q

Characteristics of Dysplasia?

A

Phleomorphism( change in size/shape)
Loss of polarity orientation)
Hyper chromatic nuclei (deep basophilic staining)
Presence of mitosis

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11
Q

Fate of dysplasia ?

A

They are pre malignant which can progress into cancer

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