Pharmocology Flashcards

1
Q

What is the chemotherapy index?

A

maximum dose tolerated by a host coupled to minimum curative dose

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2
Q

What are the mechanisums of parasite drug selectivity?

A
  • uptake or secreation
  • detoxification (host can parasite cant)
  • activation of drug
  • importance of drug target
  • binding to drug target
  • unique drug target
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3
Q

wHAT ARE THE KEY ISSUES WITH ANTI-PARASITIC AGENTS?

A
  • RE-INFECTION IN ENDEMIC AREAS
  • EXPENSIVVE
    side effects
  • environmental residue
    -resistance
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4
Q
A
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