Pharmocology Flashcards
1
Q
What is the chemotherapy index?
A
maximum dose tolerated by a host coupled to minimum curative dose
2
Q
What are the mechanisums of parasite drug selectivity?
A
- uptake or secreation
- detoxification (host can parasite cant)
- activation of drug
- importance of drug target
- binding to drug target
- unique drug target
3
Q
wHAT ARE THE KEY ISSUES WITH ANTI-PARASITIC AGENTS?
A
- RE-INFECTION IN ENDEMIC AREAS
- EXPENSIVVE
side effects - environmental residue
-resistance
4
Q
A