Pharmacology Of Male Reporductive Hormones Flashcards

1
Q

HPA male axis

A

GnRH is released in pulsitile fashion
- this causes release of LH and FSH from the pituitary

LH = testosterone from leydig cells
- levels of testosterone negative feedback on LH and GnRH

FSH = initiation of spermatogenesis in the cords and upregulates ABP production
- directly influenced via inhibin released from Sertoli cells to inhibit FSH

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2
Q

Inhibin and activin

A

Both are released by Sertoli cells

  • inhibin inhibits release of FSH
  • activin stimulates release of FSH
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3
Q

Aromatase enzyme

A

Converts androgens to estrogens

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