Pharmacology of epilepsy drugs Flashcards

1
Q

Mechanism of sodium valproate

A

+ GABA activity —> relax brain

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2
Q

Side effects of sodium valproate

A
  • tetratogenic
  • liver damage
  • hair loss
  • tremor
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3
Q

Side effects of carbamazepine

A
  • agranulocytosis
  • ## aplastic anaemia
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4
Q

Most important side effect of carbamazepine

A

P450 inducer

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5
Q

Side effects of phenytoin

A
  • folate deficiency (megaloblastic anaemia)

- vitD deficiency (osteomalacia)

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6
Q

Side effects of ethosuximide

A
  • night terrors

- rashes

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7
Q

Side effects of lamotrigine

A
  • Stevens-Johnson syndrome
  • DRESS syndrome
  • leukopenia
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