Pharmacology of epilepsy drugs Flashcards
1
Q
Mechanism of sodium valproate
A
+ GABA activity —> relax brain
2
Q
Side effects of sodium valproate
A
- tetratogenic
- liver damage
- hair loss
- tremor
3
Q
Side effects of carbamazepine
A
- agranulocytosis
- ## aplastic anaemia
4
Q
Most important side effect of carbamazepine
A
P450 inducer
5
Q
Side effects of phenytoin
A
- folate deficiency (megaloblastic anaemia)
- vitD deficiency (osteomalacia)
6
Q
Side effects of ethosuximide
A
- night terrors
- rashes
7
Q
Side effects of lamotrigine
A
- Stevens-Johnson syndrome
- DRESS syndrome
- leukopenia