Pharmacology - Mood Stabilisers Flashcards

1
Q

Lithium toxicity

A
Causes hypercalcaemia which causes constipation and fatigue
Can cause leucocytosis- high WCC
Nausea and vomiting 
Course tremor 
Nephrotoxicity 
Hypothyroidism 
Weight gain
Urinary incontinence
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2
Q

Lithium blood tests

A

Blood test done 12 hours after dose and then every 3 months

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3
Q

MAOI interactions

A

MAOI and tyramine containing foods e.g. cheese can cause a hypertensive crisis

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4
Q

MAOI side effects

A

Increase in appetite

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5
Q

Mechanism of action of lithium

A

Interferes with inositol triphosphate formation

Interferes with cAMP formation

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