Overdose Flashcards
1
Q
Dependence syndrome
A
- strong desire/craving
- difficulty controlling substance misuse
- withdrawal symptoms
- tolerance requiring increasing dose
- progressive neglect of other interests
- persisting use despite harmful consequences
2
Q
Drug induced psychosis
A
Auditory hallucinations
4+ weeks of abuse or odd ideas, drug seeking behaviour
Positive blood tests
3
Q
Opiate detoxification
A
Biopsychosocial management
Biological:
- methadone
- buprenorphine
- naltrexone
Psychological:
- CBT
- AA 12 step programme
- Family therapy
Social:
- social worker
4
Q
Why is methadone given?
A
- free therefore less likely to be involved in crime
- taken orally, reduces the risk of VTE
- most patients don’t completely abstain so best alternative
5
Q
How is methadone taken?
A
Orally
Reduce methadone 2 - 5mg every 1 - 2 weeks
Daily observed dose
6
Q
Buprenorphine mechanism of action
A
Synthetic partial agonist
Can cause liver dysfunction and intoxication
7
Q
Naltrexone mechanism of action
A
Opioid antagonist
Block euphoria
8
Q
Anti craving drugs
A
Acamprosate
9
Q
Signs of opioid toxicity
A
- pinned pupils
- drowsiness
- low BP, HR and RR
- blue and dusky coloured
10
Q
Signs of opioid withdrawal
A
- dilated pupils
- sweating
- goosebumps and shivering
- flu like symptoms
- myalgia
- stomach cramps
- diarrhoea and vomiting
- anxiety and agitation
