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Year 3 - Ageing > Pharmacology in the Elderly > Flashcards

Pharmacology in the Elderly Flashcards

1
Q

Define pharmacokinetics

A

The body’s action on the drug

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2
Q

Define pharmacodynamics

A

The drug’s action on the body

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3
Q

Give three examples of acidic drugs

A

Penicillin
Aspirin
Phenytoin

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4
Q

Give three examples of basic drugs

A

Morphine
Diazepam
Pethidine

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5
Q

Stomach pH in the elderly tends to be more… (basic/acidic)

A

Basic

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6
Q

What do acidic drugs bind to in the body?

A

Albumin

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7
Q

What do basic drugs bind to in the body?

A

Alpha-1 acid glycoprotein

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8
Q

Which do the elderly have more of: albumin or alpha-1 acid glycoprotein?

A

Alpha-1 acid glycoprotein

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9
Q

What increases the Vd of drugs in the elderly?

A

More fat compared to muscle

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10
Q

Why is hepatic metabolism reduced in the elderly?

A

Smaller liver and less blood flow

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11
Q

Why is renal excretion lower in the elderly?

A

Reduced renal blood flow and reduced tubular secretion rate

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Year 3 - Ageing (9 decks)

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