Delirium Flashcards
What is delirium?
Acute, confusional state involving memory, speech and perception problems
Give 6 examples of common delirium triggers
Dehydration Alcoholism Strong painkiller use Change in meds/environment Infection MI
What neurotransmitter is mostly affected in delirium?
ACh
Give 4 examples of direct insults to the brain which may cause delirium
Drugs
Hypoxia
Hyponatraemia
Hypoglycaemia
What tools are used to assess delirium?
CAM
4AT
What are the components of the CAM score?
Acute and fluctuating AND Inattention WITH Altered conscious OR Disorganised thinking
What are the components of the 4AT?
Alertness
AMT4
Attention
Acute or fluctating
What is the 4AT marked out of?
12
Over which score on the 4AT is suggestive of delirium?
4
What is the AMT4 part of the 4AT?
Ask age; DOB; place; current year
How do you assess attention in the 4AT?
Months of the year backwards
How is delirium managed non-pharmacologically?
Calm, well lit, quiet side room
Familiar staff and belongings
How may delirium be pharmacologically managed?
Haloperidol max 5mg PO over 24 hours
Quetiapine 25mg PO
Benzodiazepines
Sedatives
What drug is given in delirium if caused by alcohol or benzodiazepine withdrawal?
Benzodiazepine
Or if there is a seizure
Which drug is known to worsen delirium?
Lorazepam
Which receptors does haloperidol work on?
D2
In which scenarios would you give quetiapine over haloperidol in delirium?
Parkinson’s or Lewy Body Dementia
Compare the onsets of delirium, dementia and depression
Delirium - acute
Depression - abrupt
Dementia - insidious
Compare the courses of delirium, dementia and depression
Delirium - fluctuating
Dementia - progressive
Depression - worse in morning, reversible
Compare the durations of delirium, dementia and depression
Delirium - hours to month
Dementia - months to years
Depression - >2 weeks
Compare the activity levels of delirium, dementia and depression
Delirium - either sleepy and slow OR agitated and restless
Dementia - wandering, agitated
Depression - Withdrawn
Compare the alertness of delirium, dementia and depression
Delirium - fluctuating
Normal in dementia and depression
Compare the attention spans of delirium, dementia and depression
Delirium - impaired
Dementia - normal
Depression - poor concentration
Which form of dementia presents with abnormal perception and hallucinations?
Lewy Body
What are the most common hallucinations found in depression?
Third person derogatory auditory hallucinations