Pharmacology general Flashcards
Name a depolarizing paralytic
Succinylcholine
Parasympathetic stimulation would result in
Digestive secretions
What paralytic do hyperkalemic patients receive
Rocuronium
Albuterol affects
Beta 2 receptors
Dialysis patients undergoing RSI should NOT receive
Succinylcholine
Emergency treatment for hypoglycemia includes
Glucagon, Oral Glucose, D50, D10, D25
True or false: Romazicon is used as a sedative in RSI
False
Name a potent antiarrhythmic that has properties of all four classes (sodium channel blocker, potassium channel blocker, calcium channel blocker, beta-blocker).
Amiodarone
Microdrip tubing supplies how many drops per mL?
60
Name a nucleotide that slows AV nodal conduction
Adenosine
Your patient weighs 190 lbs. They need a bolus of lidocaine which is supplied in a preloaded syringe at 100 mg/5ml. Your dose is 1.5 mg/kg. How much lidocaine should you administer?
130 mg
A 72M weighing 170 lbs would receive how much Rocuronium for RSI?
7.7
You respond to a 19-year-old patient who has overdosed on her medications. She is combative and has severe tremors.
Vitals: Blood pressure160/100 mmHg, pulse132. Sinus tachycardia on the ECG. What drug class may be causing her symptoms
Amphetamines
Midazolam is supplied at 5mg/5mL. How many mL does a patient needing 3mg receive?
3
What might an overdose of morphine cause?
Hypotension and respiratory depression
What drug must be administered slowly in RSI
Fentanyl
Name a loop diuretic
Furosemide
What drug has an incredibly short half life?
Adenosine. Or Succs
Name an anticholinergic drug
Atropine, Atrovent
The time from when a drug is administered to when it reaches an effective concentration is the
Onset of action
What’s a concern in a patient taking Viagra
Hypotension
Versed dose for a 170 lb patient in RSI
6 mg
Vasoconstriction is caused by what receptors
Alpha 1
Succinylcholine onset
2-3 minutes
Naloxone is a _____ to opioid receptors
Antagonist
Amiodarone is a class ___ antidysrhythmic
III
What medication is administered for asystole
Epinephrine
Cardizem is administered at what rate
2 minutes
Aspirin MOA
Inhibits platelet aggregation
True or False: Aspirin, acetaminophen, and ibuprofen are all NSAIDs
False! Acetaminophen is not a NSAID
Your patient needs 500ml NS. You have a 10 gtts set and need to administer over an hour. What rate do you set?
83.3
1000 mg is equal to ____ grams
1
esmolol is indicated for what
As a beta blocker, it is used for hypertensive emergencies
What medication is used for eclampsia induced seizures
Magnesium Sulfate
Name a synthetic opioid with agonist and antagonist properties
Fentanyl
Atropine is
A parasympatholytic
What medication other than versed can be used for an actively seizing patient
Lorazepam
Name an adrenergic agonist that can stimulate alpha or beta receptors depending on the dose
Dopamine
Name an antidote for diltiazem overdose
Calcium Chloride
Name an antidote for magnesium sulfate overdose
Calcium Chloride
Name an antidote for TCA overdose
Sodium Bicarbonate
Name an antidote for a beta blocker overdose
Glucagon
Name an anti-histamine
Diphenhydramine
Beta 2 adrenergic stimulation leads to bronchodilation
Vessel constriction is an effect of the
Sympathetic nervous system. Alpha 1
The adrenal gland releases
Epinephrine and Norepinephrine
What drug causes wooden chest syndrome
Fentanyl
Flumazenil is an antagonist for
benzodiazepines
Medication considerations in pediatric patients includes
A faster metabolic rate than adults
Sympathomimetics
Mimic the sympathetic nervous system
Renin release is an effect of
beta 1 stimulation
Six rights of medication administration
Right medication, Right dose, Right patient, Right time, Right route, Right documentation
An antidote for opioid overdose
Naloxone
Diphenhydramine and promethazine share the adverse effect of
sedation
Droperidol causes the adverse effect of
QT prolongation and sedation
Ketamine may cause _____ in patients
hallucinations
Propofol and etomidate MOA
Modulation of GABA receptors
Glucocorticoids do what for asthma patients
Act as an anti-inflammatory agent
Benzodiazepines MOA
Binds to Type A GABA receptors, causing sedation
Hydromorphone Hydrochloride MOA
Binds to ACh receptors at the neuromuscular junction causing paralysis
Alpha 2 receptors cause
A decrease in neurotransmitter release
What drug treats anxiety and seizures
Diazepam
True or false: Montelukast is a type of glucocorticoid
False
What drug dissociates the limbic and cortical systems
Ketamine
Angiotensin II causes
Widespread vasoconstriction
Nalbuphine is an
Agonist-Antagonist
Reducing afterload in a patient with an MI is good because
reduces the workload of the heart, reducing myocardial oxygen consumption.
A muscarinic blocking drug is a
Parasympatholytic
What medications can be given to a patient with asthma
Epinephrine, Solumedrol Albuterol, Ipratropium
What drugs should be given to a cardiac arrest patient with suspected hyperkalemia
Calcium Chloride and Sodium Bicarbonate
How do you calculate drug infusion rate based on weight
Dose ordered × total volume of bag used × drip factor of IV tubing × weight in kg/total amount of drug dissolved within the bag
Glucagon causes
glycogenolysis and gluconeogenesis
Aminophylline usage may indicate
a higher dose of adenosine necessary
True or False: Expectorants are not to be used in a patient with asthma
True
Alpha agonist infiltration may cause
Tissue necrosis
Magnesium Sulfate MOA
Cerebral Vasodilation
Calcium channel blockers have a greater effect on what phase of ion exchange
Phase 0
What drug should not be administered to a hypothermic diabetic patient
D50 IVP
TXA’s government name is
Tranexamic acid
TXA must be administered within
3 hours of injury
D50 is
25g of dextrose in 50 ml of NS
D25 is
25g of dextrose in 100ml NS
D10 is
25g of dextrose in 250 ml NS
D5 is
25g of dextrose in 500 ml NS