Civilian Medications Flashcards
What is the trade name of ___
___ is a part of what drug class
What is the MOA of ___
For what is ___ indicated?
___ is contraindicated in…
What are common side effects of ___
What are precautions of ___
___ interacts with
What is the adult dose of ___
What is the pediatric dose of ___
What is the onset of ___
What is the trade name of Whole Blood?
LTOWB+
Whole Blood is a part of what drug class
Blood Component
What is the MOA of Whole Blood
Provides White blood cells, red blood cells, platelets, and clotting factors
For what is Whole Blood indicated?
Trauma with (possible) blood loss
And Hemorrhagic shock
Whole Blood is contraindicated in…
Non consent
Lack of vascular access
Non compatible
What are common side effects of Whole Blood
Pulmonary edema, Pain, Fever, Headache, Flushing,
What are precautions of Whole Blood
Administration of other drugs
Whole Blood interacts with
Lactated Ringers
What is the adult dose of Whole Blood
1 Unit
What is the pediatric dose of Whole Blood
What is the trade name of Packed Red Blood Cells
RBCs, PRBCs
Packed Red Blood Cells is a part of what drug class
Blood Component
What is the MOA of Packed Red Blood Cells
The influx of red blood cells increase the body’s oxygen transport capabilities
For what is Packed Red Blood Cells indicated?
Severe Anemia
Packed Red Blood Cells is contraindicated in…
Anemia that can be treated with other methods
Incompatible blood type
Non consent
Lack of vascular access
Non compatible
What are common side effects of Packed Red Blood Cells
Purpura, Circulatory overload, Acute lung injury, Hypersensitive reactions
What are precautions of Packed Red Blood Cells
Administration of other drugs
What is the adult dose of Packed Red Blood Cells
1 unit over 1-2 hr
What is the pediatric dose of Packed Red Blood Cells
10-15 ml/kg
What is the onset of Packed Red Blood Cells
Immediate
What is the trade name of Fresh Frozen Plasma
FFP, Octoplase
Fresh Frozen Plasma is a part of what drug class
Blood Component
What is the MOA of Fresh Frozen Plasma
Provides plasma proteins and clotting factors to body
For what is Fresh Frozen Plasma indicated?
Hemorrhage
Replacement of missing proteins
Thrombotic Thrombocytopenic Purpura
Fresh Frozen Plasma is contraindicated in…
IgA deficiency
Protein S deficiency
Hypersensitivity
Non consent
Lack of vascular access
Non compatible
What are common side effects of Fresh Frozen Plasma
Headache, Nausea, Circulatory overload, Purpura, Alkalosis, Cardiac Arrest, Tachycardia, Thromboembolism, Pulmonary edema, Vomiting
What are precautions of Fresh Frozen Plasma
Should not be used as replacement for blood loss
Administration of other drugs
Fresh Frozen Plasma interacts with
Calcium: Incompatible in same IV line
What is the adult dose of Fresh Frozen Plasma
Coagulation factor replacement: 10-15 ml/kg
Bleeding: 10-20 ml/kg
What is the pediatric dose of Fresh Frozen Plasma
Bleeding: 10-15 ml/kg
What is the onset of Fresh Frozen Plasma
Immediate
What is the trade name of Mannitol
Osmitrol
Mannitol is a part of what drug class
Osmotic Diuretic
What is the MOA of Mannitol
Increases osmotic pressure and inhibits reabsorption
For what is Mannitol indicated?
Increased ICP and Pulmonary Edema
Increased Intraocular pressure
Mannitol is contraindicated in…
Hypersensitivity
Anuria
Hypovolemia
Active intracranial bleeding
Severe pulmonary edema
What are common side effects of Mannitol
Angina, Heart failure, Tachycardia, Dehydration, low electrolyte levels, Nausea, Vomiting, Pulmonary edema, Coma, Lethargy, Acute kidney failure, Renal failure, Thirst, Alkalosis
What are precautions of Mannitol
Renal impairment
Deficient blood/brain barrier
Pregnancy & Lactation
Pediatrics
Mannitol interacts with
Digoxin: Risk of toxicity
Nephrotic drugs: Renal Failure
Neurotoxic drugs: Toxicity
What is the adult dose of Mannitol
Intracranial: 0.25 g/kg
Intraocular: 1.5-2 g/kg
What is the pediatric dose of Mannitol
Intracranial: 1-2 /kg
Intraocular: 1-2 /kg
What is the onset of Mannitol
30-60 min
What is the trade name of Phenylephrine
Neo-Synephrine, Biorphren
Phenylephrine is a part of what drug class
Vasopressor, Adrenergic
What is the MOA of Phenylephrine
Stimulates alpha-adrenergic receptors to induce vasoconstriction
For what is Phenylephrine indicated?
Hypotension from shock that does not respond to fluid replacement
Hypotension from anesthesia
Phenylephrine is contraindicated in…
Hypersensitivty
Hypovolemia
What are common side effects of Phenylephrine
Arrhythmias, Nausea, Vomiting, Blurred Vision, Headache, Tremor, Dyspnea
What are precautions of Phenylephrine
Heart Failure
Coronary artery disease
Pregnancy/Lactation
Pediatrics
Phenylephrine interacts with
General Anesthetics: Myocardial Irritability
Alpha-Adrenergic blockers, Calcium Channel blockers, Benzodiazepines, ACE inhibitors: Antagonizes vasopressor effects
MAO inhibitors, oxytocics, tricyclic antidepressants, atropine, corticosteroids: Severe hypertension
What is the adult dose of Phenylephrine
IV: 0.2 mg
IM: 2-5 mg
What is the pediatric dose of Phenylephrine
IV: 5-20 mcg
IM: 0.1 mg/kg
What is the onset of Phenylephrine
10-15 min
What is the trade name of Terbutaline
Bricanyl Turbuhaler
Terbutaline is a part of what drug class
Bronchodilator, adrenergic
What is the MOA of Terbutaline
Causes bronchodilation, prevents mast cell activation
For what is Terbutaline indicated?
Asthma induced airway disease
Terbutaline is contraindicated in…
Hypersensitivity
What are common side effects of Terbutaline
Angina, Arrhythmias, Nausea, Hypokalemia, Vomiting, Tachycardia, Myocardial ischemia, Pulmonary edema, nervousness, Tremor, headache
What are precautions of Terbutaline
Cardiac Disease
Hypertension
Hyperthyroidism
Diabetes
Glaucoma
Pregnancy
Geriatrics
Terbutaline interacts with
Adrenergics: Additive effects
MAO inhibitors: Hypertensive crisis
Beta Blockers: negates effects
What is the adult dose of Terbutaline
2.5 mg 3x daily
What is the pediatric dose of Terbutaline
2.5 mg 3x daily unless <12 yr in which case the dosage is lowered to 0.05
What is the onset of Terbutaline
PO: 60-120 min
SubQ: <15 min
What is the trade name of Pancuronium
Pavulon
Pancuronium is a part of what drug class
Nondepolarizing neuromuscular blocking agent
What is the MOA of Pancuronium
Blocks effects of acetylcholine at myoneural junction
For what is Pancuronium indicated?
Paralytic
Pancuronium is contraindicated in…
Hypersensitivity
Neonates
What are common side effects of Pancuronium
Bronchospasm, Hypertension, Tachycardia
Pancuronium interacts with
-Other paralytics, Metabolizing affecting drugs like diuretics, -Calcium Channel blockers, -Cyclosporin, Beta blockers: Prolongs duration and intensity
-Inhalation anesthetics: Enhances effects
What is the adult dose of Pancuronium
0.06-0.01 mg/kg loading dose, 0.01 mg/kg every 25-60 min maintenance
What is the pediatric dose of Pancuronium
0.06-0.01 mg/kg loading dose, 0.01 mg/kg every 25-60 min maintenance
What is the onset of Pancuronium
30-45 sec
What is the trade name of Meperidine
Demerol
Meperidine is a part of what drug class
Opioid Analgesic
What is the MOA of Meperidine
Binds to opiate receptors in the Central nervous system and produces CNS depression
For what is Meperidine indicated?
Severe pain
Sedation
Meperidine is contraindicated in…
Hypersensitivity
MAO inhibitor therapy within 14 days
Respiratory distress/difficulty
Pregnancy & Lactation
What are common side effects of Meperidine
Hypotension, Bradycardia, Flushing, Sweating, Adrenal insufficiency, Nausea, Vomiting, Confusion, Sedation, Euphoria, Headache, Seizures, Respiratory depression
Meperidine interacts with
CYP3A4 Inducer/Inhibitors
MAO inhibitors, Procarbazine: FATAL
CNS depressants and Benzos
Agonist/Antagonist analgesics
Alcohol
Neurotransmitter affecting drugs: Serotonin syndrome
What is the adult dose of Meperidine
PO: 50-150 mg every 3-4 hr
IM/SUBQ: 50-150 mg every 3-4 hr
IV: 15-35 mg/hr
What is the pediatric dose of Meperidine
PO: 1.1-1.8 mg/kg every 3-4 hr
IM/SUBQ: 1.1-1.8 mg/kg every 3-4 hr
IV:0.5-1 mg/kg loading followed by 0.3 mg/kg/hr
What is the onset of Meperidine
PO: 15 min
IM/SubQ: 10-15 min
IV: Immediate
What is the trade name of Propofol
Diprivan
Propofol is a part of what drug class
General Anesthetic
What is the MOA of Propofol
Short acting hypnotic with amnesiac effects
For what is Propofol indicated?
General anesthesia induction
Sedation
Propofol is contraindicated in…
Hypersensitivity
Pregnancy
What are common side effects of Propofol
Bradycardia, Hypotension, Hypertension, Nausea, Vomiting, Apnea, Fever, Propofol Infusion Syndrome
Propofol interacts with
Fentanyl: Severe bradycardia
Acetazolamide: Cardiorespiratory instability
Theophylline: Antagonizes effects
Alcohol, Sedative/hypnotics, opioids, antihistamines: Increased CNS depression
What is the adult dose of Propofol
40 mg every 10 min loading dose. 150-200 mcg/kg/min thereafter
What is the pediatric dose of Propofol
2.5-3.5 mg/kg
What is the onset of Propofol