Pharmacology for Obstetric Patients Flashcards by Troy Green

Q

Central Nervous System

A

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Cardiovascular

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Volume and Cardiovascular changes

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Hematological changes

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Main Hematologic effects

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Q

A

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Hepatic function

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Q

Liver function tests in normal pregnancy

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Renal changes

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Metabolic changes

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Musculoskeletal

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Definition of teratogen

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Timing of exposure

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Drugs as teratogens

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Q

Drug properties that influence placental transfer

A

Molecular weight - smaller crosses better

Iionization - ionized particles do not cross

Protein bound do not cross

Solubility to lipids cross easily

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Q

Non-obstetric surgery

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Q

Tocolytic therapy – uterine relaxation

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Q

Tocolytic – preterm labor – beta agonist

A

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Q

Tocolytic – preterm labor – beta agonist

Site of injection, dosing, and adverse effects

A

Q

Tocolytic – preterm labor – beta agonist

Anesthetic Considerations

A

Q

Tocolytic – preterm labor – CCB

A

Q

Tocolytic – preterm labor – CCB

Dosing and Anesthetic Considerations

A

Q

Preterm labor – prostaglandin inhibitors

A

Q

Preterm labor – prostaglandin inhibitors

Dosing and Anesthetic Considerations

A

Uterine relaxation - Nitroglycerin

Uterine relaxation - Nitroglycerin Adverse Effects, Dosing, and Anesthetic Considerations

Uterine relaxation – oxytocin antagonists

Oxytocin - pitocin

Oxytocin - pitocin Dosing and Adverse Effects

Methylergonovine – Methergine®

Methylergonovine – Methergine® Dosing and Anesthetic Considerations

Prostaglandins – E2, F2α, E1

Prostaglandin - F2α or carboprost

Prostaglandins

Preeclampsia

Preeclampsia treatment

Magnesium Sulfate

Magnesium Sulfate Dosing

MgSO4 - Adverse effects

Mg SO4 Anesthetic Considerations and Treatments of Toxicity

Antihypertensive agents Hydralazine and Adverse Effects

Antihypertensive agents Other Options

Risk for pulmonary aspiration

Rapid sequence intubation

Anesthesia

Post delivery