Pharmacology for Neuroanesthesia Flashcards by Troy Green

Q

IV hyperosmotic drugs

A

Order of treatment:

Mannitol
Hypertonic saline
Loop diuretics
Corticosteroids
Barbituates/Propofol

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Q

Mannitol Dosing

A

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Q

Mannitol best practices and monitoring/cautions

A

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Q

Hypertonic Saline

A

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Q

Loop diuretics - furosemide

A

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Q

Corticosteroids

A

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Q

Barbiturates and Propofol

A

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Q

Anesthesia for patients with intracranial tumors

Preoperative Management

A

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Q

Anesthesia for patients with intracranial tumors

Induction of Anesthesia

A

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Q

Anesthesia for patients with intracranial tumors

Maintenance of Anesthesia

A

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Q

Craniotomy surgical steps to consider

A

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Q

Anesthesia for craniotomy

Premedication

A

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Q

Anesthesia for craniotomy

Induction

A

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Q

Anesthesia for craniotomy

Maintenance

A

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Q

Maintenance - Hemodynamic management for craniotomy

A

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Q

Anesthesia for craniotomy

Emergence

A

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Q

Surgery for organ retrieval

A

Try to avoid pressors

Q

Acute ischemic stroke

A

Q

Seizure terminology and classifications

A

Focal (partial)
One hemisphere
Focused
“Key feature is preservation of awareness”

Generalized
Bilaterally affected
“:Abrupt onset of impaired consciousness”

Q

Antiseizure drugs - general mechanisms

A

Q

Antiseizure drugs - Drugs that inactivate Na⁺ transmission

A

Q

Antiseizure drugs - GABAnergic drugs

A

Q

Antiseizure drugs - Ca²⁺ channel modulating drugs

A

Q

Antiseizure drugs - Table showing MOA

A

Antiseizure drugs - pharmacokinetics

Antiseizure drugs - Drug interactions

Phenytoin - pharmacokinetics

Hits Vmax quickly Check sugars/electrolytes frequently

Prevention of seizures

Know duration of action of current medications, may need perioperative dose

Seizures during perioperative period

Causes of seizures in perioperative patients

Test glucose before treating!

Acute seizure management

Acute seizure management Fosphenytoin and phenytoin IV

Acute seizure managment

Status Epilepticus

[http://www.aesnet.org/about\_aes/press\_releases/guidelines2016](http://www.aesnet.org/about_aes/press_releases/guidelines2016)

Benzodiazepines

Medications for Status Epilepticus

Management of Anesthesia

Perioperative seizure activity

Relationship between pressure and volume within the cranium

Relationship between CBF and MAP