Pharmacology Basics Flashcards
how the body acts on the drug
Pharmacokinetics
how the drug affects the body
Pharmacodynamics
study of biological effects of chemicals.
Pharmacology
chemicals introduced to the body to cause changes
Drugs
The use of drugs to prevent and treat disease
Pharmacotherapeutic
What are the processes involved in Pharmacokinetics
Absorption, distribution, metabolism, and excretion of a drug
Is a scientific name that precisely describes its anatomic and molecular structure
Chemical Name
Abbreviation of the chemical name
Generic Name
These are protected by copyright
Trade Name
Where do drug comes from?
Natural and Synthetic Resources
What type of Natural resources do drugs come from?
Plants
Animals
Minerals
List down the Drug Administration Routes
- Buccal (Between cheek and gum)
- Sublingual (Under tongue)
- Translingually (On the tongue)
- Gastric
- Intravenous
- Oral
- Rectal and Vaginal
- Respiratory
is the study of the interactions
between the chemical components of living systems and the foreign chemicals, including drugs that enter those systems.
Pharmacodynamics
Drugs usually work in one of four ways:
- To replace or act as substitutes for
missing chemicals - To increase or stimulate certain
cellular activities - To depress or slow cellular
activities - To interfere with functioning of foreign cells, such as invading
microorganisms or neoplasms leading
to cell death (drugs that act in this way
are called chemotherapeutic agents)
What type of drug that interfere with functioning of foreign cells?
chemotherapeutic agents
Specific areas on cell
membranes
Receptor Sites
Interact directly with receptor sites to cause the same activity that natural chemicals would cause at that site
Agonists
How do drugs act in different ways to achieve results? (Specifically in Receptor sites)
a. Agonists
b. Inhibitors
c. Competitive antagonist
d. Non competitive antagonist
Prevent breakdown of natural chemicals that are
stimulating the receptor site
Inhibitors
React with receptor sites to block normal stimulation,
producing no effect
Competitive antagonist
React with specific receptor sites on a cell and by reacting there prevent the reaction of another chemical with a different receptor site on that cell
Non competitive antagonist
Molecules of drug A react with specific
receptor sites on cells of effector organs and change the cells’ activity
Agonist interaction with receptor site
on cell
Drug A and drug C have an affinity for
the same receptor sites and compete
for these sites; drug C has a greater
affinity, occupies more of the sites, and
antagonizes drug A.
Competitive antagonism.
Drug D reacts with a receptor site that is different from the receptor site for drug A but still somehow prevents drug A from binding with its receptor sites.
Noncompetitive antagonism.
Enzyme systems work in a (Answer), with one enzyme activating another, and then that enzyme activating another, until a cellular reaction eventually occurs.
Cascade fashion
The ability of a drug to
attack only those
systems found in foreign
cells
Selective Toxicity
