Pharmacology Flashcards
What are the 6 Rights of Medication
Person Time Medication Dose Route Documentation
percutaneous
applied to and absorbed through the skin
enteral
absorbed somewhere along the GI tract
parenteral
any route of administration that does not cause the drug to be absorbed through the skin, mucous membranes, or GI tract.
pharmacokinetics
time required for absorption
duration of action
distribution in the body
method of excretion
chemical name
describes the drug’s chemical makeup
generic name
general name for the drug
trade name
brand name
afferent nerves
carry sensory impulses from all parts of the body to the brain
efferent nerves
carry messages from the brain to the muscles and all other organs of the body.
peripheral nervous system
consists of all nervous tissue outside the brain and spinal cord and is separated into two: somatic nervous system and autonomic nervous system
autonomic nervous system
part of PNS
sends sensory impulses from internal structures (blood vessels, heart, organs) and sends them through afferent nerves to the brain.
divides into sympathetic and parasympathetic nervous systems
sympathetic nervous system
PNS-ANS
responsible for fight or flight response
key player in the regulation of hypoglycemia, hypothermia, and trauma.
what are the primary chemical messengers of the sympathetic nervous system?
norepinephrine and epinephrine
parasympathetic nervous system
PNS-ANS
rest and relaxation and digestion
ROA: topical
hours to days
ROA: oral
30-90 minutes
ROA: rectal
5-30 minutes (unpredictable)
ROA: SC injection
15-30 minutes
ROA: IM injection
10-20 minutes
ROA: SL tablet
3-5 minutes
ROA: SL spray
3 minutes
ROA: inhalation
3 minutes
ROA: IO
60 seconds
considered best alternate route if no IV access
ROA: IV
30-60 seconds
analgesics
medications that relieve pain
anesthetics
induce a loss of sensation to touch or pain
sympathomimetics
stimulate the sympathetic nervous system, by stimulating the adrenal medulla so that it releases norepinephrine and epinephrine
alpha-1 receptors
produce peripheral vasoconstriction, are associated with mild bronchoconstriction, and speed metabolism.
found in vascular smooth muscle (peripheral blood vessels, bladder neck, prostate)
alpha-2 receptors
control the release of norepinephrine
found on the pre-synaptic nerve terminals
beta-1 receptors
increase the HR, cause cardiac muscle to contract, strengthen cardiac contraction, produce automaticity, and trigger cardiac electrical conduction
found in cardiac muscle cell membrane
beta-2 receptors
stimulate vasodilation and bronchodilation
found in smooth and cardiac muscles
chronotropic
medications that affect the heart rate
inotropic
changes in the force of contraction
dromotropic
alters the velocity of the conduction of electricity through the heart
antiarrhythmic meds
sodium channel blockers
beta blockers
potassium channel blockers
calcium channel blockers
sodium channel blockers
slow the conduction through the heart
beta blockers
reduce the adrenergic stimulation of the beta receptors
potassium channel blockers
increase the heart’s contractility and work against the reentry of blocked impulses
calcium channel blockers
block the inflow of calcium into the cardiac cells, thereby decreasing the force of contraction and automaticity.