Pharmacology

Question 1

What are the mechanisms of action of Dipyridamole?

Answer 1

1. PDE inhibition
2. Adenosine uptake inhibition
   Dipyridamole is anti-platelet agent

Question 2

What is the mechanism of action of Allopurinol?

Answer 2

Reduction of urate production.

Allopurinol is a xanthine oxidase inhibitor

Question 3

What type of drug is Tirofiban, what is it used for, what is its mechanism of action and what drugs does it interact with, increasing the risk of bleeding?

Answer 3

1. It is an antiplatelet agent.
2. Used for the prevention of early myocardial infarction in patients presenting with unstable angina and NSTEMI
3. Mechanism of action: Glycoprotein IIb/IIIa inhibitor
4. Warfarin and other anticoagulants

Question 4

What is the mechanism of action of heparin

Answer 4

Antithrombin III inhibition

Question 5

What type of drug is Benzbromarone, what is it used for, what is its mechanism of action

Answer 5

It is a long acting URAT-1 inhibitor which increases excretion of uric acid by blocking its reabsorption in the kidney. It is also a non-competitive inhibitor of xanthine oxidase