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PT BOARDS - Pharma > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

Pharmacology

A

Study of substances that interact with the living system through chemicals

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2
Q

Pharmakinetics

A

Action of the body on the drugs

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3
Q

Governed by pharmacokinetics(4)

A

Absorption
Distribution
Metabolism
Elimination of drugs

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4
Q

Absorption: 2 primary routes

A
  1. Enteral

2. Parenteral

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5
Q

Enteral administration

A

Through the alimentary canal

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6
Q

3 types of enteral administration

A
  1. Oral
  2. Sublingual
  3. Rectal
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7
Q

Parenteral administration

A

Not through alimentary canal

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8
Q

2 types of parenteral administration

A

Inhilation and injection

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9
Q

Intravenous

A

Fast absorption

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10
Q

Intramuscular

A

Deltoid
Vastus lateralis
Gmax

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11
Q

Intra arterial

A

Dx procedure

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12
Q

Subcutaneous

A

Local response

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13
Q

Distribution

A

Drug will bind to a protein (ie albumin)

Then it will attach to the receptor and is synthesized in the liver

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14
Q

Warfarin (coumadin)

A

99% protein bound

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15
Q

Albumin

A

Synthesized in the liver

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16
Q

Bioavailability

A

Percent of drug molecules that reaches the bloodstream

i.e. 100g Aspirin = 50 g = 50%

17
Q

Metabolism

A

Process of breaking down drig molecules

18
Q

First pass metabolism

A

Liver (before it mix in the circulation it should pass first in the liver)

  • has enzyme that decreases the effect of the drug
  • from inactive to active form
19
Q

Main site of elimination

A

KIDNEYS

20
Q

Half-life

A

Amount of time for the remaining 50% of drug molecule to be eliminated

21
Q

Half-life of antibiotics

A

3 hours

22
Q

Half life of biogesic

A

2 hours

23
Q

Pharmacodynamics

A

Action of drugs in the body

24
Q

2 drug receptors (pharmacodynamics)

A

AGONIST DRUG

ANTAGONIST DRUG

25
Q

Agonist drug

A

Bind to a specific receptor that activate/stimulate

26
Q

Antagonist drug

A

Will bind then block/deactivate

PT BOARDS - Pharma (11 decks)

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