Pharmacology Flashcards
What drugs should be avoided in patients with a sulfa allergy?
“Sulfa Pills Frequently Cause Terrible Allergy Symptoms”
Sulfonamides
Probenicid
Furosemide
Celecoxib
Thiazides
Acetazolamides
What drugs can cause Steven-Johnson Syndrome
“Steve Jobs made APPLE PC’s”
Allopurinol
phenytoin
phenobarbital
lamotrigine
ethosuxamide
penicillin
carbamazapine
Sulfonamides
What is the MOA of Bosentan?
Bosentan is a competitive antagonist of endothelin-1 receptors
Clinical Use: pulmonary hypertension
What is the treatment of choice for trigeminal neuralgia?
carbamazepine is the first line treatment for trigeminal neuralgia
Other therapies include oxcarbazepine, baclofen and lamotrigine
What drugs are CYP450 inhibitors?
“CRACK AMIGOS”
Cimetidine, Ritonavir, Amiodarone, Ciprofloxacin, Ketoconazole
Acute Alcoholism, Macrolides, Isoniazid, Grapefruit juice, Omeprazole, Sulfonamides
CYP450 inhibitors
What drugs are CYP450 inducers?
Guiness, Corona, and PBRs induce chronic alcoholism
Griseofulven, Carbamazapine, Phenytoin, Barbituarits, St. John’s Wart, Chronic Alcoholism