Pharmacology Flashcards
which drug isn’t used in the secondary prevention following MI
furosemide
which drug can cause hyperkalaemia
ramipril
which drug doesn’t interact pharmacodynamically with other drugs to cause hypotension
simvastatin
effect of rifampicin on ethylestriadol
unchanged Km and higher Vmax
which drug doesn’t need to be used with caution in px with renal impairment
omeprazole
drug that exhibits first order elimination kinetics administered b constant IV infusion
steady state plasma concentration is achieved when the rate of administration equals the rate of elimination
apparent volée of distribution
knowledge of it allows the calculation of a loading dose
drug with a half life of 4 hours
within a few mins plasma concern 10mg/L
concen of drug after 24 hours is
0.161 mg/L
for a drug thats hows first order elimination kinetics which one of the following will not occur if its dosage via the oral route at administration is double
doubling the half life
drug X has first order elimination kinetics and has a half life of 6h
if administered by constant IV infusion how long will it take for the plasma concen to reach approx 94% of its final steady state concen
24 hours
sildenafil and isosorbide mononitrate leads to what
postural hhypotension
what can exacerbate gout when px is on allopurinol
furosemide
grapefruit and statins
muscle pains
what drug may be decreased by impaired renal function
furodemide
on warfarin for AFib. mod arthritic pain what drug should be given
paracetamol
