Immunology Flashcards
NK cells are part of what immunity
innate - don’t require prior learning to know which cells to kill
complement system and lectin pathyway
allows bacteria to be better eliminated by coating sugars on their surface through binding proteins such as MBL
LNs and spleen are what
clearing zones where foreign material presented by dendritic cells can result in rapid degeneration of lymphocytes highly selective for the microbe bearing that material
The formation of memory B cells accounts for what
rapid production of IgG at re exposure to a microbe after vaccination
Why can infections sustained in severe combined immunodeficiency resemble that of advanced stage HIV
because CD4 T helper cells are massively reduced in both conditions
why do old people get shingles
because they have immune senicence
granulomas are formed as a what
protective encasement by the interplay of interferon gamma secreting T lymphocytes and Interlukin 12 secreting macrophages
biologics such s Anti TNF represent a form of what
passive immunisation
delayed hypersensitive lumps together various pathologies such as
contact h/s
granulomatous reactions
complex immune dysfunction
multiple episodes of small infections which resolve with antibiotics and rest
15yo
common variable immunodeficiency
what aspects are essential to explore either primary or secondary immunodeficiency
detailed account of diet
smoking status
fam hx of DM and infections
ANA levels are good for what and not so good for what
good for auto immune causes
not so good for immunodefic
ANA levels are never indicated in who
someone with lots of infections
patients with asplenia should get what
regular inactivated vaccinations against pneumonia, HI, meningitis and influenza
what kinds of vaccinations are contraindicated in asplenia
live vaccine
