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Internal Medicine > Pharmacology > Flashcards

Pharmacology Flashcards

1
Q

Bleomycin SE

A

Pulmonary fibrosis

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2
Q

Cyclophosphamide SE

A

Hemorrhagic cystitis

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3
Q

Isoniazid SE

A

Vit B6 deficiency, lupus-like syndrome, liver toxicity

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4
Q

Cyclosporine SE

A

Renal toxicity

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5
Q

ACE inhibitors SE

A

Cough; angioedema

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6
Q

Demeclocycline SE

A

Diabetes Insipidus

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7
Q

Sulfa drugs SE

A

Allergies, kernicterus in neonates

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8
Q

Halothane SE

A

Liver necrosis

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9
Q

Local anesthetic SE

A

Seizures

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10
Q

Phenytoin SE

A

Teratogen, folate deficiency, hirsutism

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11
Q

Vincristine SE

A

Peripheral neuropathy

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12
Q

Amiodarone SE

A

Thyroid dysfunction, pulmonary toxicity

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13
Q

Valproic acid SE

A

NTD in offspring

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14
Q

Thioridazine SE

A

Retinal deposits, cardiac toxicity

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15
Q

Vancomycin SE

A

Red man’s syndrome

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16
Q

Clofibrate SE

A

Increased GI neoplasms

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17
Q

Tetracyclines SE

A

Photosensitivity, teeth staining in children

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18
Q

Quinolones SE

A

Teratogens (cartilage damage)

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19
Q

Quinidine (Class 1A antiarrhythmic) SE

A

Cinchonism (HA, tinnitus, vertigo), thrombocytopenia, QT prolongation

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20
Q

Morphine SE

A

Sphincter of Oddi spasm

21
Q

Clindamycin SE

A

Pseudomembranous colitis

22
Q

Chloramphenicol SE

A

Aplastic anemia, gray-baby syndrome ( in premature infants b/c they lack liver UDP-glucuronyl transferase)

23
Q

Doxorubicin SE

A

Cardiomyopathy

24
Q

Busulfan SE

A

Pulmonary fibrosis

25
Q

MOA inhibitors

A

Tyramine HTN crisis after eating cheeses or wine

26
Q

Hydralazine SE

A

Lupus-like syndrome

27
Q

Procainamide SE

A

Lupus-like syndrome

28
Q

Minoxidil SE

29
Q

Chlorpropamide SE

30
Q

Oxytocin SE

31
Q

Opiates SE

32
Q

Didanosine SE

A

Pancreatitis, peripheral neuropathy

33
Q

Halogen anesthesia SE

A

Malignant hyperthermia

34
Q

Succinylcholine SE

A

Malignant hyperthermia

35
Q

Zidovudine SE

A

Bone marrow suppression

36
Q

Digitalis SE

A

GI disorders, vision changes, arrhythmias

37
Q

SSRI SE

A

Anxiety, agitation, insomnia, sexual dysfunction

38
Q

Warfarin SE

A

Necrosis, teratogen

39
Q

Simvastatin SE

A

Liver and muscle toxicity

40
Q

Ethambutol SE

A

Optic neuritis

41
Q

Cisplatin SE

A

Nephrotoxicity

42
Q

Methyldopa SE

A

Hemolytic anemia (Coombs test -positive)

43
Q

Benzodiazepines antidote

A

Flumazenil

44
Q

Beta blockers antidote

45
Q

Cholinesterase inhibitors antidote

A

Atropine, pralidoxime

46
Q

Copper or gold antidote

A

Penicillamine

47
Q

Lead antidote

A

EDTA or succimer in children

48
Q

Methanol or ethylene glycol antidote

A

Fomepizole or ethanol

49
Q

Muscarinic blockers antidote

A

Physostigmine

Internal Medicine (12 decks)

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