Pharmacology Flashcards
What are side effects of Midazolam administration?
Decreased LOC leading to:
- Respiratory depression
- Loss of airway control
- Hypotension
What is the usual dose of Midazolam for seizures?
0.1mg/kg IM, repeat after 10 mins PRN
What are the actions of Midazolam?
- Anticonvulsant - reduces seizure activity
- Minor tranquilizer
- Muscle relaxant
What is the time of onset for Midazolam?
IM - 2-5 mins
What is the duration of action for Midazolam?
IM - 2-3 hours
What are the contraindications for Midazolam?
- Known hypersensitivity
What are the precautions for Midazolam administration?
2,
- Haemodynamic instability
- Respiratory depression
What is the presentation of Midazolam?
5mg in 5mL or 15mg in 3mL glass ampoules
What type of drug is Midazolam?
S4 - Anticonvulsant and sedative agent, benzo
What type of drug is Aspirin?
NSAID - S2
What is the presentation of Aspirin?
300mg tablet
What are the actions of Aspirin?
- Inhibits platelet function for up to 7 days
2. Suppresses inflammation, reduces fever, relieves pain (rapidly absorbed from the stomach and small bowel).
What is the use for Aspirin in paramedic practice?
In suspected myocardial ischaemia - reducing platelet aggregation and limiting clot development
What are the adverse effects of Aspirin?
- Allergic reaction - asthma, angioneurotic oedema, urticaria, rhinitis, shock)
- Aggravation of bleeding tendencies
- Gastric irritation (unlikely with 1 tablet)
What are the contraindication to Aspirin administration?
- Known or suspected allergy to salicylates
- known or suspected active bleeding
- known bleeding tendency
- Chest pain associated with psychostimulant overdose (due to increased risk of cerebral haemorrhage).
