Pharmacology Flashcards
4 Types of Drug Names
Chemical Name
Generic Name
Trade Name/Brand Name
Official Name
5 Drug Sources
Plants Animals Minerals Microorganisms Synthetic
Dose
The amount of a drug to be administered
Dosage
Size, Number and Frequency of a drug to be administered.
Pharmacokinetics
How medication enter the body, how they reach the site of action and how they become eliminated.
Types of Drug Routes
Enteral
Perenteral
Enteral Drug Routes
Through the G.I. Track. Can be administered orally, rectally, oral gastric, nasal gastric, sublingually and bucally.
Parenteral Drug Routes
Intravenous, Intramuscular, Intradermal, Intracardiac, Intraosseous, Subcutaneous, Umbilically, Transdermally, Endotracheal, Inhalation and Sublingual Injection.
3 Kinds of Transport
Active Transport, Passive Transport and Facilitated Transport
Facilitated Transport
Uses helper proteins to complete carrier mediated diffusion.
Factors that affect medication absorption
solubility, concentration, pH, surface area, site of administration blood supply and bioavailability.
2 Physiological barriers
Blood brain barrier
Placenta barrier
Half Life
How long it takes for half of a drug to be eliminated from the body.
Pharmacodynamics
The mechanism by which drugs act to produce physiological changes.
Passive Transport
osmosis, diffusion and filtration
Active Transport
Uses ATP to complete transport.
Affinity
A drug is drawn to a receptor site.
Efficacy
A drug can bind a receptor and cause an action or effect.
Agonist
A drug that binds a receptor causing the intended reaction of that receptor.
Partial Agonist
A drug that binds a receptor and causes part of that receptors intended reaction.
Inverse Agonist
A drug that binds a receptor and causes an opposite reaction from what the receptor is intended for.
Competitive Antagonist
A drug that binds a receptor and competes with an agonist to displace it.
Antagonist
A drug that binds a receptor and causes NO effect.
Antagonist/Agonist
A drug that binds a receptor and blocks only a portion of the intended reaction.
Ex. Blocks A and causes B to have intended reaction.
Non-competitive Antagonist
A drug that binds a receptor and displaces any agonist that is present.
Partial Antagonist
A drug that binds a receptor and blocks some of the intended response but not all of it.