Pharmacology 2 Flashcards
Emollients
-used in ? to do ?
-dry and scaly conditions e.g. eczema to enhance rehydration of the epidermis
Topical steroids
- effect
- used in
- SE
- vasoconstrictive, anti inflammatory and anti proliferative
- eczema, psoriasis, Keloid scars, non-infective inflammatory dermatosis
- skin thinning, purpura, stretch marks, steroid rosacea, telangectasia, perioral dermatitis
Antiseptics
- effect
- used in
- e.g.
- bacteriocidal/bacteriostatic
- recurrent infections, wound irrigation, antibiotic resistance
- Chlorhexidine, Triclosan, hydrogen peroxide
Topical antibiotics
-4 examples of use and drugs
- Acne (Clindamycin, Erythromycin, tetracyclin)
- Rosacea (metronizadole)
- Impetigo (mupirocin, fusidic acid)
- infected eczema (combined corticsteroid/ antibacterial)
Antivirals
- e.g
- 3 examples of uses
-valaciclovir (topical)
-Herpes simplex (topical)
Eczema Herpeticum
Herpes Zoster
Antifungals
-3 uses and example
-Candida (Nystatin, clotrimazole)
Dermatophytes (ringworm) (clotrimazole terbinafine cream)
Pityriasis versicolor (Ketoconazole)
Antipruritics
4 examples
Menthol (dermacool)
Capsaicin
Camphor Iphenol
Crotamiton (Eurax cream)
Keratolytics
- general use
- 4 uses
-Used to soften keratin
-Viral warts e.g. salicylic acid
hyperkeratotic eczema + psoriasis
Corns
To remove Keratin plaques in scalp
Wart treatment
Mechanical paring + Keratolytics/ Formaldehyde/ Glutanaldehyde/ Silver nitrate/ cryotherapy
podophyllin (genital)
Topical Psoriasis treatment
-scalp Psoriasis
Emollients \+ Coal tar Vit D analogue Keratolytic topical steroids Dithranol
-Greasy ointment to soften scale
Tar shampoo
steroids in alcohol base
Vit D analogues
Imiquimob
- What is it
- action
- uses
- imadazoquinoline amine
- immune response modulator, enhances innate and cell mediated immunity
- anti viral and anti tumour so genital warts and superficial BCC
calcineurin inhibitors
- e.g.
- action
- use
- Tacrolimus
- Suppress lymphocyte activation
- Treat atopic eczema
