pharmacology Flashcards
what is pharmacodynamics
effects of drugs in the body
what is pharmacokinetics
how the drug moves through the body
what are the 4 components of pharmacokinetics
absorption
distribution
metabolism
excretion
what is the target of B-lactams
penicillin binding proteins
how do B-lactams work
affect the synthesis of the peptidoglycan layer of the cell wall
are B-lactams bacteriostatic or bactericidal
bactericidal
when should penicillin V be taken and why
sensitive to stomach acid
should be taken 30 mins before food or 3 hours after
what are the components of co-amoxiclav
clavulanic acid and amoxicillin
what is ceftolozane + tazobactam used to treat
resistant UTIs`
what kind of antibiotic is vancomycin
glycopeptide
is vancomycin bactericidal or bacteriostatic
bactericidal
what is a ligand
a substance that is bound to a protein
what is affinity
the tendency of a ligand to bind to its receptor
what is an antagonist
a drug that reduces the action of another drug
what is the potency of a drug
the concentration or amount of a drug needed to produce the desired effect