pathology Flashcards
how does hypoxic injury cause cellular swelling
reduced sodium pump activity causes isoosmotic gain of water
what is the cell type change called in barretts oesophagus
metaplasia
what is metaplasia
reversible change of one differentiated cell type to another
what usually causes metaplasia
chronic irritation or inflammation
what is dysplasia
abnormal cell growth and differentiation
what is atrophy
decreased size or number of cells
what is coagulative necrosis
cells retain shape and structure giving the tissue a firm texture
what is colliquative necrosis
tissue becomes liquified due to enzymatic breakdown of cells
what is autolysis
where tissue begins to rot / break itself down
name 2 ways in which neutrophils move
contracting cytoplasmic microtubules
chemotaxis
name the 3 steps of how we get neutrophils from blood to the tissue
margination
adhesion
emigration
what causes exudate
increased vascular permeability and increased net flow of fluid out of the vessels
exudate is primarily responsible for which cardinal sign of inflammation
swelling
what is the predominant inflammatory cell type in pus
neutrophil
which metastatic route involves tumour cells moving across a body cavity
transcoelomic