microbiology Flashcards
what is colonisation
presence of microbe in the human body without an inflammatory response
what is an infection
inflammation due to a microbe
what is bacteraemia
presence of viable bacteria in the blood
what is bacteriuria
presence of viable bacteria in urine
what is used to treat MRSA
vancomycin
what does MIC stand for
minimum inhibitory concentration
what is MIC
the concentration of antibiotic needed in tissue for bacteria to not grow anymore
what is beta haemolysis
complete haemolysis
what is alpha haemolysis and what colour does it turn
partial haemolysis
turns green
what is gamma haemolysis
no haemolysis
what is a clinical breakpoint
the chance of reaching MIC with the normal doses - whether a bug is susceptible to a drug or not
what is the criteria for septic shock
DESPITE ADEQUATE FLUID RESUS
- persistent hypotension requiring vasopressors to maintain MAP greater than or equal to 65 mmHg AND
- lactate greater than or equal to 2 mmol/l
what are the 5 pillars of inflammation
calor
rubor
dolor
tumor
functio laesa
acronym for the first management of sepsis
BUFALO
what does BUFALO stand for
blood cultures
urine output
fluids
antibiotics IV
lactate
oxygen