Pharmacology Flashcards

1
Q

Which recreational drug is a risk factor for MI?

A

Cocaine

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2
Q

For which cancer types does the COCP have a protective effect?

A

Ovarian, endometrial, colorectal

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3
Q

Which vitamin is folate?

A

B9

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4
Q

Which vitamin is thiamine?

A

B1

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5
Q

What rheumatic disease contraindicates COCP?

A

SLE with antiphospholipid antibodies

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6
Q

Absorption of iron?

A

10% of oral dose

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7
Q

Malaria treatment in pregnancy?

A

Artesunate

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8
Q

What is the mechanism of action of ulipristal acetate?

A

Selective progesterone modulator with partial antagonist effect

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9
Q

SE of therapy with ulipristal acetate?

A

Progesterone receptor modulator associated endometrial change

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10
Q

HRT benefits

A

Control of menopausal symptoms
Maintenance of BMD
Reduced risk CAD
Reduced risk Alzheimer’s when estrogen started early
Reduced risk colorectal cancer
Reduced risk T2DM

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11
Q

Minimum duration of oral progesterone to provide endometrial protection?

A

12-14 days

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12
Q

Cyclizine drug class?

A

H1 antagonist

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13
Q

Drug to reduce fetal transmission of toxoplasmosis?

A

Spiramycin

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14
Q

Which drug inhibits breakdown of cAMP thereby promoting smooth muscle relaxation?

A
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15
Q

Reduction of Fe3+ to Fe2+ is inhibited by?

A

Tea

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16
Q

Reduction of Fe3+ to Fe2+ is inhibited by?

A

Tea

17
Q

How many hours pre-delivery can pethidine cause neonatal respiratory depression?

A

2h

18
Q

What kind of drug is misoprostol?

A

Prostaglandin E1 analog

19
Q

What kind of drug is carboprost (Hemabate)?

A

Prostaglandin F2 alpha analog

20
Q

COCP effect on hormone profile?

A

Lower FSH, LH, E2
No change AMH

21
Q

What is the prodrug of 6-mercaptopurine?

A

Azathioprine

22
Q

Toxoplasmosis treatment?

A

Spiramycin if no fetal infection
Pyrimethamine/sulphadiazine/folinic acid if fetal infection