Pharmacology Flashcards
A 22-year-old woman is brought to the emergency department. On examination, the
patient is sweaty, jaundiced, and lethargic, with marked right upper quadrant
tenderness. Transaminase (AST and ALT) values are markedly elevated. A serum
toxicology screen is sent. The case was diagnosed as acute acetaminophen toxicity.
Which of the following is the specific antidote for this case?
A. Protamine sulphate
B. Naloxone
C. N-acetylcysteine
D. Pralidoxime
C. N-acetylcysteine
Several new drugs are being tested
for their effects on β2-adrenergic
receptor. The investigator plots an
S-shaped curve of the activity of
adenylate cyclase vs. drug dose in
response to drug A and drug D.
Which of the following describes
comparison between drug A and
drug D regarding the efficacy and
the potency?
A. Drug A is less effective.
B. Drug A is more potent
C. Drug D is more effective.
D. Drug D is more potent
D. Drug D is more potent
A 17-year-old high school student is brought to the emergency department after
feeling a tearing sensation in his knee when he was tackled playing football. After the
initial consult, it is determined that the boy will need surgery to reattach a torn
ligament. During anesthesia, a long-acting competitive neuromuscular blocking drug
(NMB) is given. Could you identify this drug?
A. Succinylcholine
B. Metocurine
C. Mivacurium
D. Dantrolene
B. Metocurine
A 13-year-old white girl with a past medical history of nasal polyps develops severe
bronchoconstriction and wheezing after taking a large dose of aspirin, having
mistaken it for a cold medication. After presenting to the emergency department, she
is found to have a past history of aspirin allergy. Which of the following medications
is a leukotriene receptor antagonist that can be used effectively to stop the
bronchoconstriction resulting from her aspirin allergy?
A. Pranlukast
B. Theophylline
C. Prednisone
D. Salbutamol
A. Pranlukast
