Pharmacology Flashcards
Common Antiemetic Serotonin Antagonist names and end
Dolasetron
Ondansetron
Tropisetron
TRON
Common Antiemetic Dopamine Antagonist names and end
Promethazine
Prochlorperazie
AZINE
Common antihistamines
Diphenhydramine
Dimenhydrinate
Meclizine
Antihistamine MOA
H1 Receptor antagonists
PPI
Proton pump inhibitors
Stop acid at the pump
PPI names and ending
Omeprazole
Lansoprazole
Pantoprazole
ZOLE
PPI long term use causes what deficiency
B12
ED meds moa
Increase nitric oxide which opens penis blood vessels
ED med side efects
headache
flushing
blurred vision
back pain
due to vessel dilation
ED meds are contraindicated in people who have
Blood vessel problems
Heart problems
BP problems
Iron supplements can cause _ of skin and teeth
STAINING
Iron and Vit C
AVOID
IroniC
Iron and food
1hr before unless GI upset
Iron and stool
Dark green or black
Iron rich foods
Liver
Egg yolk
Muscle meat
Yeast
Statins treat
Hypercholesterolemia
prevent coronary events
MIs
Strokes
increases HDL
LDL is _
HDL is_
BAD
Good
you want Ldl to be _ and Hdl to be _
LOW
HIGH
Statin meds
Atorvastatin
Simvastatin
Pravastatin
ALL statins like
Lovastatin (Mevacor) due damage to
Liver and Muscles
How often to monitor liver on statins
q12w then q6m
Statins hit the liver to avoid
ALCOHOL
Neuropathy and Myopathy and Statins
breakdown
will feel weakness, pain, tingling, tenderness
H of heparin
Heparin sodium prevents fibrin
given IV or SQ
E of heparin
Enoxaparin
low-molecular weight heparin, given SQ
P of heparin
Protamine sulfate
antidote
A of heparin
administer to prevent clot formation
R of heparin
Risk for bleeding
gum bleeds, bruises, hematuria, petechia
I of heparin
Instruct client to avoid
Corticosteroids, Salicylates, NSAIDs, green leafy veg
N of heparin
Normal aPTT is 20-36 seconds
therapeutic level is 1.5 to 2 times that, so 60 to 80 seconds
C of coumadin
Coagulation interference via antagonizing K
O of coumadin
Oral administration
U of coumadin
Use contraindicated in clients with low platelets or uncontrolled bleeding
M of Coumadin
Mephyton aka Vit K, antidote
A of coumadin
Avoid Vit K
Avoid these meds
Acetaminophen, glucocorticoids, aspirin
D of coumadin
Doses are once Daily
I of coumadin
INR and PT monitor
PT should be 1.5 to 2 times control
INR should be 2-3 times control
N of coumadin
NO for pregos
Heparin OK
Heparin and Coumadin and Anticoagulants not
Antiplatelet
Antiplatelet meds
CAP
Clopidogrel
Aspirin
Pentoxifylline
Antiplatelet prevent
By
MIs and Stroke
preventing platelet clumping
For anticoagulants and antiplatelet watch for
take with
BLEEDING
FOOD
Anticoagulant and antiplatelet meds should not be taken if pt has what problems
Peptic ulcers - bleed
Renal/hepatic problems - cant process
Most common S/S of hemorrhage
Weakness
Dizziness
Headache
S/S of bleeding precaution
Coffee ground emesis
Tarry stool
Bruising
petechiae
bleeding gums
What med enhances bleeding
NSAIDs
Corticosteroids increase _ effects
Aspirin
AVOID together
After thrombolytic therapy give
Beta Blockers
this decreases myocardial oxygen consumption
Echinacea treats
Common cold
Echinacea messes with what meds
TB
HIV
Cancer
Ginger root treats
Nausea
Motion sickness
RA
Ginger root messes with
Platelets
Pregnancy
Ginkgo Biloba use
vasodilation
mental processes
Dementia and Alzheimer’s
Ginkgo biloba messes with what meds
antihistamines
antidepressants
antipsychotics
coagulation
Valerian use
Increases GABA
Insomnia
Valerian side effects
Depression
Not for pregos
We’ll CLIMB TO THE PEAK starting FAST and ending SLOW
for insulin
Fastest insulin
onset
peak
duration
Lispro
15m
30m to 1h
3 to 4h
Fast insulin
onset
peak
duration
Regular
30m to 1h
2 to 3h
5 to 7h
Intermediate insulin
onset
peak
duration
NPH insulin
1 to 2h
4 to 12h
18 to 24h
Long acting insulin
onset
peak
duratin
Glargine
1h
NONE
10 to 24h
Metoclopramide pyramidal symptoms
spasms
twitching
restless ness
Metoclopramide slows
gastric motility
Beta 2 receptors
causes smooth muscle relaxation, which may result in peripheral vasodilation with subsequent hypotension and reflex tachycardia. Stimulation of beta-2 receptors in the lungs causes bronchodilation, the desired clinical effect.
Beta blockers
Beta blockers work mainly by slowing down the heart. They do this by blocking the action of hormones like adrenaline. Beta blockers usually come as tablets.
Beta blocker side effects
feeling tired, dizzy or lightheaded, cold fingers or toes
Can you take Beta2 Blockers with Asthma
NO
ACE inhibitors meds
A pril
lisinopril etc
Can you take ACE inhibitors with K+
NO
Salicylate acid thearpy cntraindications
Third trimester pregnancy
Thrombocytopenia
Adolescents with chickenpox
Levothiroxine in older adults increases risk for
Fractures
Vancomycin adverse effect infusion reaction
Ren Man Syndrome
Rashes, flushing, tachycardia, hypotension
Zosin meds like doxazosin are _ blocker
they…
Alpha
relax muscles easing urinary retention and hypertension
Benzodiazepines can affect what organ
EYES
be careful with eye conditions like glaucoma
Montelukast 101
use for
when to take
Anti inflammatory
Asthma
once daily at bedtime
What do vasopressins for diabetic insipidus pts do?
Inreace reabsorption of water in renal tubules
Before giving blood document
base line vitals
Isosorbide mononitrate use
NITRATE
long term prophylaxis against heart attacks