Pharmacological Principles Flashcards

0
Q

Agonists

A

Drug that is capable of binding with receptors to induce a cellular response

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1
Q

Affinity

A

Chemical attraction that impels certain molecules to unite with others to form complexes

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2
Q

Antagonist

A

Drug that blocks the response of another drug

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3
Q

Bioavailability

A

Ability of a drug to reach the bloodstream and it’s target tissues

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4
Q

Botanical

A

Plant extract used to treat or prevent illness

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5
Q

Pharmacologic Classification

A

Mechanism of organizing drugs on the basis or their mechanism of action

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6
Q

Therapeutic classification

A

Method for organizing drugs on the basis of their clinical usefulness

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7
Q

Combination drug

A

Drug product with more than one active generic ingredient

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8
Q

Complementary and alternative therapies

A

Treatments considered outside the realm of conventional western medicine

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9
Q

Controlled substance

A

In the us, a drug whose use is restricted by the Comprehensive Drug Abuse Prevention and Control Act; in Canada, a drug subject to guidelines outlined in the Canadian Narcotic Control Act

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10
Q

Dependence

A

Strong physiological or psychological need for a substance

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11
Q

Dietary supplement

A

Nondrug substance regulated by the Dietary Supplement Health and Education Act of 1994 (DSHEA)

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12
Q

Efficacy

A

The ability of a drug to produce a desired response

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13
Q

Formulary

A

List of drug and drug recipes commonly used by pharmacists

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14
Q

Generic name

A

Nonproprietary name of a drug assigned by the government

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15
Q

Holistic

A

Viewing a person as an integrated biologic, psychosocial, cultural, communicating whole, exists ohm and functioning within the communal environment

16
Q

Loading dose

A

Comparatively large dose given at the beginning of a treatment to rapidly obtain the therapeutic effect of a drug

17
Q

Mechanism of action

A

The way in which a drug exerts its effects

18
Q

Pharmacopoeia

A

Medical reference indicating standards of drug purity, strength, and directions for synthesis

19
Q

Pharmacogenetics

A

Area of pharmacology that examines the role of genetics in drug response

20
Q

Plasma half life (t 1/2)

A

The length of time required for the plasma concentration of a drug to decrease by half after administration

21
Q

Polypharmacy

A

The taking of multiple drugs concurrently

22
Q

Potency

A

The strength of a drug specified concentration or dose

23
Q

Receptor

A

The structural component of a cell which a drug binds in a dose-related manner, to produce a response

24
Q

Scheduled drug

A

In the United States, a term describing a drug placed into one of five categories based on its potential for misuse or abuse

25
Q

Teratogen

A

Drug or other agent that causes developmental birth defects

26
Q

Therapeutic index

A

The ratio of drugs LD50 to its ED50

27
Q

Therapeutic range

A

The dosage range or serum concentration that achieves the desired drug effects

28
Q

Toxic concentration

A

level of drug that will result in serious adverse effects

29
Q

Trade name

A

Proprietary name of a drug assigned by the manufacturer; also called the brand name or product name

30
Q

Withdraw

A

Physical signs of discomfort associated with the discontinuation of an abused substance

31
Q

OTC

A

Over the counter

32
Q

FDA

A

Food and Drug Administration

33
Q

Ophthalmic route

A

Used to treat local conditions of the eye and surrounding structures

34
Q

Otic route

A

Used to treat local conditions of the ear, including infections and soft blockages of the auditory canal

35
Q

Transdermal

A

The use of transdermal patches provides an effective means of delivering certain medications. Examples include nitroglycerin for angina pectoris and scopolamine for motion sickness