Pharmacokinetics – “What the body does to the drug” Flashcards
1
Q
Absorption
A
the process of a substance entering the blood circulation
2
Q
Distribution
A
the dispersion or dissemination of substances throughout the fluids and tissues of the body.
3
Q
Metabolism (or Biotransformation)
A
the irreversible transformation of parent compounds into daughter metabolites; liver is the primary site
4
Q
Excretion
A
the removal of the substances from the body; in rare cases, somedrugsirreversibly accumulate inbody tissue.
5
Q
Onset
A
the time it takes to reach the minimum effective concentration after a drug is administered
6
Q
Peak Effect
A
occurs when the drug reaches its highest blood or plasma concentration
7
Q
Duration
A
the length of time the drug has a pharmacologic effect
