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Pharmacology > pharmacodynamics > Flashcards

pharmacodynamics Flashcards

1
Q

agents that act on specific enzymes

A

Asprin, methotrexate, tranylcypromine, nitroglycerin, heparin, imitinib, infliximab

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2
Q

Asprin

A

acts on specific enzymes. inhibits cyclooxygenase

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3
Q

methotrexate

A

acts on specific enzymes. inhibits dihydrofolate reductase. antineoplastic (cancer)

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4
Q

tranylcypromine

A

acts on specific enzymes. inhibits monoamine oxidase. antidepressent.

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5
Q

nitroglycerin

A

acts on specific enzymes. activates guanylate cycline. for treating angina

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6
Q

heparin

A

acts on specific enzymes. activates antithrombin. antigoagulant

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7
Q

imitinib

A

acts on specific enzymes. inactivates a protein kinase. leukemia

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8
Q

infliximab

A

acts on specific enzymes. binds to TNF. arthritis

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9
Q

agents that act on trasport systems

A

cocaine, chlorothiazide, fluoextine, omeprazole

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10
Q

cocaine

A

acts on transport. nhibits norepinephrine reuptake by neuron

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11
Q

chlorothiazide

A

acts on transport. diuretic, blocks inhibits transport of Na and Cl by kidney tubule

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12
Q

fluoxetine

A

acts on transport. inhibits serotonin reuptake by neurons. antidepressent

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13
Q

omeprazole

A

acts on transport. inhibits H transport by parietal cells. decreases stomach acid.

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14
Q

agents that act on ion channels

A

nifedipine, minoxidil, procaine

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15
Q

nifedipine

A

acnts on ion channels. Ca channl blocker. antihypertensive

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16
Q

minoxidil

A

acts on ion channels. increases K uptake by cells. antihypertensive

17
Q

procaine

A

acts on ion channels. local anesthetic. inhibits Na channels

18
Q

agents that act on cell membrane receptors

A

propranolol, cimetidine, prazosin, morphine .insulin

19
Q

propranolol

A

acts on cell membrane. blocks beta adrenergic receptor. antihypertensive.

20
Q

cimetidine

A

acts on cell membrane. blocks histamine receptors. decreases stomach acid

21
Q

prazosin

A

acts on cell membrane. blocks alpha 1 receptors in blood vessels. antihypertensive

22
Q

morphine

A

acts on cell membrane. activates opiate receptors. pain

23
Q

insulin

A

acts on cell membrane. activates insulin receptor. diabetes.

24
Q

agents that act on intracellular receptors

A

steroids. glucocorticoids, cortisol (anti-inflammatory)

Pharmacology (5 decks)

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