PHARMACEUTICAL SOLVENTS Flashcards
Pharmaceutical solvents
Water
Alcohol
Glycerin
Propylene glycol
Fixed oils
Most common and preferred solvent
Water
Used for aqueous DF except sterile DF
Purified water
Purified water is _x more free of dissolved solid than is water
100x
Obtained by distillation, ion-exchange or reverse osmosis
Purified water
% content of alcohol to act as preservative
> 10%
Second most common solvent
Alcohol
Can dissolve many water insoluble substances
Alcohol
Prevent microbial growth
Alcohol
Imparts a characteristic taste and odor
Alcohol
Has undesired pharmacological and potential toxic effects when ingested
Alcohol
Clear, syrupy fluid
Glycerin
Glycerin is _ with water and alcohol
MISCIBLE
Humectant, emollient and preservative
Glycerin
Substitute for glycerin
Propylene glycol