METHOD OF FILLING AEROSOLS Flashcards
1
Q
Method of Filling Aerosols
A
Cold Filling
Pressure Filling
2
Q
In cold filling, both the product concentrate & propellant must
be cooled to
A
-34.5°C to -40°C
3
Q
The products is quantitatively placed in the aerosol container, the valve assembly is inserted & crimped into place, & the liquefied gas, under pressure, is metered into the valve stem form a pressure burette.
A
Pressure filling
4
Q
Used for most pharmaceutical aerosols
A
Pressure filling
5
Q
- Less danger of moisture contamination of the product
- Less propellant is lost in the process
A
Two advantages of pressure filling over cold filling