Pharma Psycho II

Question 1

BZD dependence treatment

Answer 1

Lorazepam IV, or Alprazolam PO

Question 2

BZD withdrawal treatment

Answer 2

diazepam
or
chlordiazepoxide

Question 3

Neuroanatomic origin of the +tive psychotics symptoms. And receptors

Answer 3

Mesolimbic
D2C-Receptor
blocking it will prevent symptoms

Question 4

-tive psychotics symptoms receptors

Answer 4

5HT1 driven by serotonin.

blocking it will prevent symptoms

Question 5

typical anti psychotics side effects, at nigrostiatal

Answer 5

EPS

Question 6

typical antipsychotics side effects, at Tuboinfundibular tract

Answer 6

men: gynecomastia
women: galactorhea and menorrhea

Question 7

typical antipsychotics ACH side effects

Answer 7

dry mouth, urinary retention

Question 8

Typical Antipsycothics on descending order of potency and side effects incidence

Answer 8

Haloperidol- Fluphenazin, thioridazine, chlorpromazine

Question 9

Quetiapine SE

Answer 9

somnolence. Tho, is good to reat insomnia, bipolar/mania
Lower incidence of movement disorders; appropriate for
use in patients with existing movement disorders

Question 10

Olanzapine SE

Answer 10

Greater incidence of diabetes and weight gain; avoid in

diabetic and obese patients.

Question 11

SE Risperidone

Answer 11

Greater incidence of movement disorders. EPS

Question 12

SE Ziprasidone

Answer 12

Increased risk of prolongation of QT interval; avoid in

patients with conduction defects

Question 13

SE Clozapine

Answer 13

High risk of agranulocytosis; need to monitor CBC on

regular basis; cardiomyopathy

Question 14

SE Aripiprazole

Answer 14

Compulsive behavior (gambling)

Question 15

Safer antipsychotic for use in pregnant patients

Answer 15

Lurasidone

Question 16

SE of all atypical

Answer 16

QTC prolongation, ACH side effect. Do a 12 lead EKG before and after Tx

Question 17

Whats the best medication at treating SE symptoms of AtipicalAntiPsy

Answer 17

clozapine. Best drug we got but most lethal.

Question 18

Requirements to use Clozapine

Answer 18

Last resource. need to have failed at least two anti-phsyc. Not worked on max doses and get CBC weekly, monthly. if SE, change to other

Question 19

Antipsychotic election drug for a regular, cooperative patient

Answer 19

atypical PO

Question 20

Antipsychotic election drug for non-compliant patient + agitated

Answer 20

IM: olanzapine, haloperidol “The B52 shot”

Question 21

Antipsychotic election drug for patients that wont swallow pills

Answer 21

Disolving tablets : olanzapine, risperidon

Question 22

Antipsychotic election drug for chornic non compliant patient

Answer 22

Depot form: olanzapine, risperidon-

Question 23

Antipsychotic election drug for patient that has failed to everything else

Answer 23

Clozapine

Question 24

first-line agents for smoking cessation.

Answer 24

Varenicline

Bupropion (not in bulimia, nor other seizure risky disease)