Pharma Psycho II Flashcards
BZD dependence treatment
Lorazepam IV, or Alprazolam PO
BZD withdrawal treatment
diazepam
or
chlordiazepoxide
Neuroanatomic origin of the +tive psychotics symptoms. And receptors
Mesolimbic
D2C-Receptor
blocking it will prevent symptoms
-tive psychotics symptoms receptors
5HT1 driven by serotonin.
blocking it will prevent symptoms
typical anti psychotics side effects, at nigrostiatal
EPS
typical antipsychotics side effects, at Tuboinfundibular tract
men: gynecomastia
women: galactorhea and menorrhea
typical antipsychotics ACH side effects
dry mouth, urinary retention
Typical Antipsycothics on descending order of potency and side effects incidence
Haloperidol- Fluphenazin, thioridazine, chlorpromazine
Quetiapine SE
somnolence. Tho, is good to reat insomnia, bipolar/mania
Lower incidence of movement disorders; appropriate for
use in patients with existing movement disorders
Olanzapine SE
Greater incidence of diabetes and weight gain; avoid in
diabetic and obese patients.
SE Risperidone
Greater incidence of movement disorders. EPS
SE Ziprasidone
Increased risk of prolongation of QT interval; avoid in
patients with conduction defects
SE Clozapine
High risk of agranulocytosis; need to monitor CBC on
regular basis; cardiomyopathy
SE Aripiprazole
Compulsive behavior (gambling)
Safer antipsychotic for use in pregnant patients
Lurasidone
SE of all atypical
QTC prolongation, ACH side effect. Do a 12 lead EKG before and after Tx
Whats the best medication at treating SE symptoms of AtipicalAntiPsy
clozapine. Best drug we got but most lethal.
Requirements to use Clozapine
Last resource. need to have failed at least two anti-phsyc. Not worked on max doses and get CBC weekly, monthly. if SE, change to other
Antipsychotic election drug for a regular, cooperative patient
atypical PO
Antipsychotic election drug for non-compliant patient + agitated
IM: olanzapine, haloperidol “The B52 shot”
Antipsychotic election drug for patients that wont swallow pills
Disolving tablets : olanzapine, risperidon
Antipsychotic election drug for chornic non compliant patient
Depot form: olanzapine, risperidon-
Antipsychotic election drug for patient that has failed to everything else
Clozapine
first-line agents for smoking cessation.
Varenicline
Bupropion (not in bulimia, nor other seizure risky disease)
