Childhood Disorders+ Mood &+

Question 1

Only ______________
are FDA-approved for treatment of
irritability in ASDs.

Answer 1

risperidone and aripiprazole

Question 2

ADHD Dx Criteria

Answer 2

The symptoms must
be present for more than 6 months and usually appear before the age of 7.
Symptoms must be present in at least 2 areas, such as home and school.

Question 3

ADHD is associated with lower levels of _____________

Answer 3

dopamine

Question 4

ADHD First-line treatment

Answer 4

methylphenidate and

dextroamphetamine.

Question 5

ADHD Second-line treatment

Answer 5

atomoxetine, a norepinephrine reuptake
inhibitor with fewer side effects and less risk of abuse. The alpha-2 agonists clonidine and guanfacine can also been used, because they enhance cognition
and attention in the prefrontal cortex.

Question 6

for ADHD, On the USMLE Step 2 CK, _______ is usually chosen over the
first-line treatment, given the side-effect profiles of those
treatments

Answer 6

atomoxetine

Question 7

Tourette Disorder Dx Criteria

Answer 7

characterized by the onset of multiple tics, lasting more

than one year, and is seen before the age of 18.

Question 8

Tourette Disorder Tx

Answer 8

dopamine antagonists: haloperidol, pimozide, and risperidone. Clonidine, an alpha-2 agonist, can also be used.

Question 9

MDD is associated with

decreased ________ neurotransmitter(s)

Answer 9

norepinephrine, serotonin, dopamine, and REM
latency
increased REM

Question 10

MDD Dx Cx

Answer 10

2-weeks
depressed mood or anhedonia + 4 of
SIGECAPS

Question 11

MDD 1st L TX

Answer 11

SSRI

Question 12

MDD Tx: If no effect after 4 weeks of SSRI_____

Answer 12

, switch to other SSRI.

Question 13

MDD Tx: If some improvement is noted, but not full response of the
SSRI?

Answer 13

increase the dose of the SSRI.

Question 14

MDD 2nd L TX

Answer 14

SNRIs

Question 15

Patient with
depression and
neuropathic pain TX

Answer 15

duloxetine,

Question 16

TX OF Patient with
depression who is
fearful of weight gain
or sexual side effects
or is a smoker trying
to quit

Answer 16

bupropion,

Question 17

Bipolar Disorder TX. If acute mania

Answer 17

, use lithium,

Question 18

Bipolar Disorder TX. If acute mania with severe symptoms

Answer 18

atypical antipsychotics

(lithium or valproate) PLUS antipsychotic: AMBOSS

Question 19

DIG FAST meaning

Answer 19

Distractibility, Irresponsibility, Grandiosity, F​light of ideas, Activity increase, Sleep deficit, Talkativeness

Question 20

bipolar depression, TX

Answer 20

lithium, quetiapine, lurasidone, or lamotrigine

Question 21

bipolar depression, TX in pregnancy

Answer 21

Lurasidone. but risk of fetal EPS at 3rd trimester

Question 22

Persistent Depressive Disorder TX

Answer 22

antidepressant medications and psychotherapy.

Question 23

Cyclothymic Disorder TX

Answer 23

lithium, valproic acid or antipsychotic medication, and psychotherapy

Question 24

Major Depressive Disorder with Atypical Features TX

Answer 24

SSRIs or MAOIs***
MAOIs are the correct answer on USMLE Step 2 CK for the
treatment of atypical depression.

Question 25

Major Depressive Disorder with Seasonal Pattern

Answer 25

phototherapy and bupropion or SSRIs.

Question 26

Postpartum
blues or
“baby
blues” Tx

Answer 26

Supportive,

usually selflimited

Question 27

Depressive
disorder
with
peripartum
onset

Answer 27

Antidepressant

medications

Question 28

Brief
psychotic
disorder with
peripartum
onset

Answer 28

Antipsychotic
medication,
lithium, and
possibly hospital admission

Question 29

Bereavement (Grief) Tx

Answer 29

psychotherapy. Pharmacotherapy is the wrong answer

Question 30

Serotonin Syndrome Tx

Answer 30

Stop SSRI medication.
Symptomatic treatment of fever, diarrhea, hypertension
Cyproheptadine (serotonin antagonist)