Mood Stabilizers

Question 1

Valproate Side Effects

Answer 1

Spina Bifida
Pancreatitis
↓platelets
agranulocytosis
Tremors, weight gain
Alopecia

Question 2

Valproate Toxicity features:

Answer 2

hyponatremia, coma or death.

Question 3

Lamotrigine Side Effects

Answer 3

Stevens-Johnson syndrome

Question 4

Electroconvulsive therapy

(ECT)Side Effects

Answer 4

Headaches, transient memory loss

Question 5

Mention the Tricyclic antidepressants

Answer 5

Doxepin
amitriptyline, nortriptyline,
imipramine

Question 6

Tricyclic antidepressants Side Effects

Answer 6

Hypo/hypertension, dry mouth, constipation,
confusion, arrhythmias, sexual side effects,
weight gain, GI disturbances

Question 7

Mention the Monoamine oxidase inhibitors

Answer 7

phenelzine,
isocarboxazid,
tranylcypromine

Question 8

Monoamine oxidase inhibitors Side Effects

Answer 8

Monitor diet, given that food rich in tyramine will
produce hypertension. Safe foods include white
wine and processed cheese. Unsafe foods
include red wine, aged cheese, and chocolate

Question 9

Mention the Monoamine Serotonin selective

reuptake inhibitors

Answer 9

fluoxetine, paroxetine,
sertraline, (es)citalopram,
, fluvoxamine

Question 10

SSRI side effects

Answer 10

Headaches, weight changes, sexual side

effects, GI disturbances

Question 11

Mention the Serotonin norepinephrine

reuptake inhibitors

Answer 11

(des)venlafaxine, duloxetine

Question 12

Serotonin norepinephrine

reuptake inhibitors, side effects

Answer 12

“saffer” Hypertension, blurry vision, weight changes,

sexual side effects, GI disturbances

Question 13

bupropion, side effects

Answer 13

increased risk for seizures

Question 14

trazodone, side effects

Answer 14

priapism,

Question 15

mirtazapine,side effects

Answer 15

weight gain

and sedation.

Question 16

Lithium , side effects

Answer 16

Tremors, weight gain, GI disturbance,
nephrotoxic, teratogenic, leukocytosis,
diabetes insipidus.

Question 17

how can Lithium cause toxicity?

Answer 17

Lithium has a narrow therapeutic index. Blood
levels should be monitored.
Severe toxicity gives confusion, ataxia, lethargy,
and abnormal reflexes.

Question 18

Serotonin Syndrome treatment

Answer 18

Stop SSRI medication.
Symptomatic treatment of fever, diarrhea, hypertension
Cyproheptadine (serotonin antagonist)