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Trisha's Board Review Flash Cards > Pharma : Cardiac Drugs (mostly) > Flashcards

Pharma : Cardiac Drugs (mostly) Flashcards

1
Q

Antiarhythmic Drugs : Prototype Group IB

A

Lidocaine

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2
Q

Antiarhythmic Drugs : Prototype Group IC

A

Flecainide

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3
Q

Antiarhythmic Drugs : Prototype Group 2

A

Propranolol and Esmolol

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4
Q

Antiarhythmic Drugs : Prototype Group 3

A

Dofetilide and Ibutilide

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5
Q

Antiarhythmic Drugs : Prototype Group 4

A

Verapamil

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6
Q

Anticonvulsant sometimes classified as group 1b because it can reverse diitalis-induced arrhythmias

A

Phenytoin

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7
Q

Amiodarone is a group 3 antiarrhythmic but can also be classified as…

A

Group 1A

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8
Q

This drug has the greatest action potential prolonging block. (Which ion curren is it blocking?)

A

Amiodarone

Potassium

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9
Q

This drug when given with digoxin will increase serum concentration of digoxin?

A

Quinidine

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10
Q

Quinidine, drug that prolongs AP duration, is associated with what new arryhthmia?

A

Torsades de pointes

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11
Q

Which drug is most likely to precipitate arrhythmias? (Proarrhythmic effect)

A

Flecainide

Group 1c

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12
Q

Antiarrhythmic drug group used to reduce progression of heart failure and as prophylaxis from new onset arrhythmias post MI?

A

Group 2

B Blockers

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13
Q

Antiarrhythmic drug which blocks spdium, calcium, and potassium channels and B adrenoceptors?

A

Amiodarone

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14
Q

Drug of choice for abolishing av nodal arrhythmias?

A

Adenosine

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15
Q

Nonselective B blockers

A

Propranolol and timolol

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16
Q

B1 selective B blockers

A

Atenolol, acebutolol, metoprolol

Possibly leas hazardous in asthmatic patients

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17
Q

B blockera with partial agonist effect

A

Acebutolol and pindolol

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18
Q

B blocker which lacks lical anesthetic effect

A

Timolol

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19
Q

B blocker with low lipid solubilty

A

Atenolol

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20
Q

Shortest acting b blocker

A

Esmolol

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21
Q

Longest acting b blocker

A

Nadolol

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22
Q

B blocker with combined a blockade

A

Carvedilol, labetolol

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23
Q

Antiarhythmic Drugs : Prototype Group IA

A

Procainamide

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24
Q

Antiarrhythmic with logest half life

A

Amiodarone

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25
Which antiarrhythmic drug can cause sle like symptoms?
Procainamide
26
Which antiarrhythmic drug has cinchonism (headache, vertigo, tinnitus) as toxicity?
Quinidine
27
Most suitable therapy for acute arrrhthymia in patient with thyrotoxicosis?
Esmolol (b blockers)
28
Procainamide toxicity antidote
Sodium lactate
29
Which antiarrhythmic drug is useful in digoxin-induced arrhythmias and acute MI arrhythmias?
Lidocaine
30
On ECG, prolonged PR interval, qrs and qt interval is caused by...
Group 1a
31
Prolonged pr interval and qt interval is caused by
Sotalol (group 3)
32
``` Cholesterol gallstones may be a side effect of these lipid lowerig agents except Cholysteramine Clofibrate Bezafibrate Gemfibrozil Ezetimibe ```
Ezetimibe
33
What drug inhibits lipolysis in adipose tissu consequently reducing. Hepatic VLDL in curculation?
Niacin
34
Most effective to decrease LDL
HMG-CoA reductase inhibitors (statins)
35
Most effecive to reduce triglycerides
Fibrates (gemfibrozil, clofibrate, bezafibrate, fenofibrate)
36
MOA of fibrates in lipid lowering
Upregulating lipoprotein lipase
37
Statins inhibit which cholesterol precursor
Mevalonate
38
Site of action of ezetimibe
Small intestine brush border
39
Drugs you could use to control BP in pheochromocytoma
Phenoxybenzamine, phentolamine, labetalol
40
Tx for rebound hypertension caused by clonidine
Phentolamine
41
Antidote to cyanide poisoning
Inhaled amyl nitrite + IV sodium nitrite + IV sodium thiosulfate
42
Cyanide affects what portion ETC?
Complex IV (cytochrome oxidase)
43
``` Cholesterol gallstones may be a side effect of these lipid lowerig agents except Cholysteramine Clofibrate Bezafibrate Gemfibrozil Ezetimibe ```
Ezetimibe
44
What drug inhibits lipolysis in adipose tissu consequently reducing. Hepatic VLDL in curculation?
Niacin
45
Most effective to decrease LDL
HMG-CoA reductase inhibitors (statins)
46
Most effecive to reduce triglycerides
Fibrates (gemfibrozil, clofibrate, bezafibrate, fenofibrate)
47
MOA of fibrates in lipid lowering
Upregulating lipoprotein lipase
48
Statins inhibit which cholesterol precursor
Mevalonate
49
Site of action of ezetimibe
Small intestine brush border
50
Drugs you could use to control BP in pheochromocytoma
Phenoxybenzamine, phentolamine, labetalol
51
Tx for rebound hypertension caused by clonidine
Phentolamine
52
``` Cholesterol gallstones may be a side effect of these lipid lowerig agents except Cholysteramine Clofibrate Bezafibrate Gemfibrozil Ezetimibe ```
Ezetimibe
53
What drug inhibits lipolysis in adipose tissu consequently reducing. Hepatic VLDL in curculation?
Niacin
54
Most effective to decrease LDL
HMG-CoA reductase inhibitors (statins)
55
Most effecive to reduce triglycerides
Fibrates (gemfibrozil, clofibrate, bezafibrate, fenofibrate)
56
MOA of fibrates in lipid lowering
Upregulating lipoprotein lipase
57
Statins inhibit which cholesterol precursor
Mevalonate
58
Site of action of ezetimibe
Small intestine brush border
59
Drugs you could use to control BP in pheochromocytoma
Phenoxybenzamine, phentolamine, labetalol
60
Tx for rebound hypertension caused by clonidine
Phentolamine
61
``` Cholesterol gallstones may be a side effect of these lipid lowerig agents except Cholysteramine Clofibrate Bezafibrate Gemfibrozil Ezetimibe ```
Ezetimibe
62
What drug inhibits lipolysis in adipose tissu consequently reducing. Hepatic VLDL in curculation?
Niacin
63
Most effective to decrease LDL
HMG-CoA reductase inhibitors (statins)
64
Most effecive to reduce triglycerides
Fibrates (gemfibrozil, clofibrate, bezafibrate, fenofibrate)
65
MOA of fibrates in lipid lowering
Upregulating lipoprotein lipase
66
Statins inhibit which cholesterol precursor
Mevalonate
67
Site of action of ezetimibe
Small intestine brush border

Trisha's Board Review Flash Cards (25 decks)

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