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Trisha's Board Review Flash Cards > Pharma : Cardiac Drugs (mostly) > Flashcards

Pharma : Cardiac Drugs (mostly) Flashcards

1
Q

Antiarhythmic Drugs : Prototype Group IB

A

Lidocaine

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2
Q

Antiarhythmic Drugs : Prototype Group IC

A

Flecainide

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3
Q

Antiarhythmic Drugs : Prototype Group 2

A

Propranolol and Esmolol

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4
Q

Antiarhythmic Drugs : Prototype Group 3

A

Dofetilide and Ibutilide

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5
Q

Antiarhythmic Drugs : Prototype Group 4

A

Verapamil

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6
Q

Anticonvulsant sometimes classified as group 1b because it can reverse diitalis-induced arrhythmias

A

Phenytoin

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7
Q

Amiodarone is a group 3 antiarrhythmic but can also be classified as…

A

Group 1A

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8
Q

This drug has the greatest action potential prolonging block. (Which ion curren is it blocking?)

A

Amiodarone

Potassium

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9
Q

This drug when given with digoxin will increase serum concentration of digoxin?

A

Quinidine

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10
Q

Quinidine, drug that prolongs AP duration, is associated with what new arryhthmia?

A

Torsades de pointes

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11
Q

Which drug is most likely to precipitate arrhythmias? (Proarrhythmic effect)

A

Flecainide

Group 1c

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12
Q

Antiarrhythmic drug group used to reduce progression of heart failure and as prophylaxis from new onset arrhythmias post MI?

A

Group 2

B Blockers

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13
Q

Antiarrhythmic drug which blocks spdium, calcium, and potassium channels and B adrenoceptors?

A

Amiodarone

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14
Q

Drug of choice for abolishing av nodal arrhythmias?

A

Adenosine

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15
Q

Nonselective B blockers

A

Propranolol and timolol

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16
Q

B1 selective B blockers

A

Atenolol, acebutolol, metoprolol

Possibly leas hazardous in asthmatic patients

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17
Q

B blockera with partial agonist effect

A

Acebutolol and pindolol

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18
Q

B blocker which lacks lical anesthetic effect

A

Timolol

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19
Q

B blocker with low lipid solubilty

A

Atenolol

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20
Q

Shortest acting b blocker

A

Esmolol

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21
Q

Longest acting b blocker

A

Nadolol

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22
Q

B blocker with combined a blockade

A

Carvedilol, labetolol

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23
Q

Antiarhythmic Drugs : Prototype Group IA

A

Procainamide

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24
Q

Antiarrhythmic with logest half life

A

Amiodarone

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25
Q

Which antiarrhythmic drug can cause sle like symptoms?

A

Procainamide

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26
Q

Which antiarrhythmic drug has cinchonism (headache, vertigo, tinnitus) as toxicity?

A

Quinidine

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27
Q

Most suitable therapy for acute arrrhthymia in patient with thyrotoxicosis?

A

Esmolol (b blockers)

28
Q

Procainamide toxicity antidote

A

Sodium lactate

29
Q

Which antiarrhythmic drug is useful in digoxin-induced arrhythmias and acute MI arrhythmias?

A

Lidocaine

30
Q

On ECG, prolonged PR interval, qrs and qt interval is caused by…

A

Group 1a

31
Q

Prolonged pr interval and qt interval is caused by

A

Sotalol (group 3)

32
Q 
Cholesterol gallstones may be a side effect of these lipid lowerig agents except
Cholysteramine
Clofibrate
Bezafibrate
Gemfibrozil
Ezetimibe
A

Ezetimibe

33
Q

What drug inhibits lipolysis in adipose tissu consequently reducing. Hepatic VLDL in curculation?

A

Niacin

34
Q

Most effective to decrease LDL

A

HMG-CoA reductase inhibitors (statins)

35
Q

Most effecive to reduce triglycerides

A

Fibrates (gemfibrozil, clofibrate, bezafibrate, fenofibrate)

36
Q

MOA of fibrates in lipid lowering

A

Upregulating lipoprotein lipase

37
Q

Statins inhibit which cholesterol precursor

A

Mevalonate

38
Q

Site of action of ezetimibe

A

Small intestine brush border

39
Q

Drugs you could use to control BP in pheochromocytoma

A

Phenoxybenzamine, phentolamine, labetalol

40
Q

Tx for rebound hypertension caused by clonidine

A

Phentolamine

41
Q

Antidote to cyanide poisoning

A

Inhaled amyl nitrite + IV sodium nitrite + IV sodium thiosulfate

42
Q

Cyanide affects what portion ETC?

A

Complex IV (cytochrome oxidase)

43
Q 
Cholesterol gallstones may be a side effect of these lipid lowerig agents except
Cholysteramine
Clofibrate
Bezafibrate
Gemfibrozil
Ezetimibe
A

Ezetimibe

44
Q

What drug inhibits lipolysis in adipose tissu consequently reducing. Hepatic VLDL in curculation?

A

Niacin

45
Q

Most effective to decrease LDL

A

HMG-CoA reductase inhibitors (statins)

46
Q

Most effecive to reduce triglycerides

A

Fibrates (gemfibrozil, clofibrate, bezafibrate, fenofibrate)

47
Q

MOA of fibrates in lipid lowering

A

Upregulating lipoprotein lipase

48
Q

Statins inhibit which cholesterol precursor

A

Mevalonate

49
Q

Site of action of ezetimibe

A

Small intestine brush border

50
Q

Drugs you could use to control BP in pheochromocytoma

A

Phenoxybenzamine, phentolamine, labetalol

51
Q

Tx for rebound hypertension caused by clonidine

A

Phentolamine

52
Q 
Cholesterol gallstones may be a side effect of these lipid lowerig agents except
Cholysteramine
Clofibrate
Bezafibrate
Gemfibrozil
Ezetimibe
A

Ezetimibe

53
Q

What drug inhibits lipolysis in adipose tissu consequently reducing. Hepatic VLDL in curculation?

A

Niacin

54
Q

Most effective to decrease LDL

A

HMG-CoA reductase inhibitors (statins)

55
Q

Most effecive to reduce triglycerides

A

Fibrates (gemfibrozil, clofibrate, bezafibrate, fenofibrate)

56
Q

MOA of fibrates in lipid lowering

A

Upregulating lipoprotein lipase

57
Q

Statins inhibit which cholesterol precursor

A

Mevalonate

58
Q

Site of action of ezetimibe

A

Small intestine brush border

59
Q

Drugs you could use to control BP in pheochromocytoma

A

Phenoxybenzamine, phentolamine, labetalol

60
Q

Tx for rebound hypertension caused by clonidine

A

Phentolamine

61
Q 
Cholesterol gallstones may be a side effect of these lipid lowerig agents except
Cholysteramine
Clofibrate
Bezafibrate
Gemfibrozil
Ezetimibe
A

Ezetimibe

62
Q

What drug inhibits lipolysis in adipose tissu consequently reducing. Hepatic VLDL in curculation?

A

Niacin

63
Q

Most effective to decrease LDL

A

HMG-CoA reductase inhibitors (statins)

64
Q

Most effecive to reduce triglycerides

A

Fibrates (gemfibrozil, clofibrate, bezafibrate, fenofibrate)

65
Q

MOA of fibrates in lipid lowering

A

Upregulating lipoprotein lipase

66
Q

Statins inhibit which cholesterol precursor

A

Mevalonate

67
Q

Site of action of ezetimibe

A

Small intestine brush border

Trisha's Board Review Flash Cards (25 decks)

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