Pharma Cancer Flashcards

1
Q

Alkylating agent treatment for lymphoma

A

Cyclophosphamide

Rescue: MESNA

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2
Q

Alkylating agent treatment for colon cancer

A

Cisplatin

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3
Q

Alkylating agent treatment for brain tumors

A

Carmustine

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4
Q

Antimetabolite treatment for lymphomas and GTN

A

Methotrexate

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5
Q

Antimetabolite tretament of acute leukemia

A

6-mercaptopurine

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6
Q

Antimetabolite treatment for colorectal and skin cancer, which causes thymine-less death of cells

A

5-Flurouracil

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7
Q

Antimetabolite treatment of CML in blast crisis

Most specific for the S phase of the cell cycle

A

Cytaribine

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8
Q

Inhibits ribonucleotide reductase
Treatment of pancreatic Cancer
Antimetabolite

A

Gemcitabine

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9
Q

Prevents microtubule assembly

A

Vincristine

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10
Q

Podophyllotoxin
Inhibits topoisomerase II
Treatment of lung Cancer, NHL, GTN

A

Etoposide

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11
Q

Camptotecin
Inhibits DNA topoisomerase I
Treatment of small cell lung cancer

A

Topotecan

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12
Q

Taxane which prevents microtubule disassembly

Advanced breast and ovarian cancer

A

Paclitaxel

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13
Q

Intercalating agent which causes dilated cardiomyopathy

A

Doxorubizine

Rescue: Dexrazoxane

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14
Q

Treatment of testicular cancer

A

Bleomycin

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15
Q

Treatment of melanoma, Wilms tumor, and GTN

A

Actinomycin D

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16
Q

Tyrosine kinase inhibitor for the treatment of CML

A

Imatinib (Gleevec)

17
Q

Treatment of metastatic breast cancer

Active against cells expressing HER-2/neu

A

Trastuzumab

18
Q

Inhibits VEGF

Treatment of metastatic Cancer

A

Bevacizumab

19
Q

differentiation therapy
treatment of acute promyelocytic leukemia
Vitamin

A

ATRA