Pharma Cancer Flashcards
Alkylating agent treatment for lymphoma
Cyclophosphamide
Rescue: MESNA
Alkylating agent treatment for colon cancer
Cisplatin
Alkylating agent treatment for brain tumors
Carmustine
Antimetabolite treatment for lymphomas and GTN
Methotrexate
Antimetabolite tretament of acute leukemia
6-mercaptopurine
Antimetabolite treatment for colorectal and skin cancer, which causes thymine-less death of cells
5-Flurouracil
Antimetabolite treatment of CML in blast crisis
Most specific for the S phase of the cell cycle
Cytaribine
Inhibits ribonucleotide reductase
Treatment of pancreatic Cancer
Antimetabolite
Gemcitabine
Prevents microtubule assembly
Vincristine
Podophyllotoxin
Inhibits topoisomerase II
Treatment of lung Cancer, NHL, GTN
Etoposide
Camptotecin
Inhibits DNA topoisomerase I
Treatment of small cell lung cancer
Topotecan
Taxane which prevents microtubule disassembly
Advanced breast and ovarian cancer
Paclitaxel
Intercalating agent which causes dilated cardiomyopathy
Doxorubizine
Rescue: Dexrazoxane
Treatment of testicular cancer
Bleomycin
Treatment of melanoma, Wilms tumor, and GTN
Actinomycin D