Pathology Historology

Question 1

Abnormal azurophilic primary granules

Answer 1

Toxic granules - Sepsis (severe infection)

Question 2

Patches of dilated ER that appear as sky-blue cytoplasmic puddles

Answer 2

Dohle bodies - Severe infection

Question 3

Distinctive needle like azurophilic granules found in myeloblasts

Answer 3

Auer rods - AML, NHL, Thyroid cancer

Question 4

Scarrered macrophages with abdundant wrinkled greenblue cytoplasm

Answer 4

Sea-blue histiocytes - CML

Question 5

Small lymphocytes disrupted in the process of making smears

Answer 5

Smudge cells - CLL

Question 6

Large cells with multiple nuclei or a single nucleus with multiple nuclear lobes

Answer 6

Reed Sternberg cells - Hodgkin cell

Question 7

Nuclear remnants are phagocytosed by interspersed cells with abundant clear cytoplasm or lipid droplets

Answer 7

Starry sky pattern - Burkitts lymphoma

Question 8

Cells found in adult Tcell lymphoma which appear to have multilobulated nuclei

Answer 8

Cloverleaf or flower cells - Adults t-cell lymphoma

Question 9

Destructive plasma cell tumors involving axial skeleton

Answer 9

Plasmocytoma - Multiple myeloma

Question 10

Multiple nuclei, prominent nuclei, and cytoplasmic droplets containing Ig

Answer 10

Bizzare multinucleated cells - multiple myeloma

Question 11

Fiery red cytoplasm

Answer 11

Flame cells - Multiple myeloma

Question 12

Pink cytoplasmic inclusions

Answer 12

Russell Bodies - Multiple myeloma

Question 13

Blue globular nuclear inclusions

Answer 13

Dutcher bodies - Multiple myeloma

Question 14

M proteins causes RBCs in PBS to stick in linear arrays

Answer 14

Rouleaux condormation - Multiple myeloma

Question 15

Erythroblasts with ironladen mitochondria visible as perinuclear granules

Answer 15

Ringed Sideroblasts - Sideroblastic anemia, INH, Lead, copper poisoning, Multiple myeloma, RA, B6 deficiency

Question 16

Neutrophils with only two nuclear lobes

Answer 16

Pseudo-pelger Huet cells - MDS

Question 17

Megakaryocytes with single nuclear lobes or multiple separate nuclei

Answer 17

Pawn ball megakaryocytes - MDS

Question 18

Premature release of nucleated erythroid and early granulocyte progenitors

Answer 18

Leukoerythroblastosis - Primary myelofibrosis

Question 19

Cells that were probably damaged during the birthing process in the fibrotic marrow

Answer 19

Tear drop cells or dacryocytes - Primary myelofibrosis

Question 20

Pentalaminar tubules often with a dilated terminal end or tennis racket like appearance

Answer 20

Birbeck granules - Langerhans cell histiocytosis

Question 21

Small yellowbrown, brown or rustcolored foci in the spleen

Answer 21

Gandy gamma nodules - Splenic congestion

Question 22

Small hyperchromic RBC lacking central pallor

Question 23

Small dark nuclear remnants present in RBCs of asplenic patients

Answer 23

Howell Jolly bodies

Question 24

Membrane bound precipitates on denatured globin chains

Answer 24

Bite cells - G6PD

Question 25

RBCs shaped like curved blades

Answer 25

Sickle cells - Sickle cell anemia

Question 26

Dehydrated cells with bulls eye appearance

Answer 26

Target cells - B thalassemia, sickle cell anemia

Question 27

Fragmented RBCs called helmet cells if cut in half

Answer 27

Schistocytes - RBC trauma, DIC, HUS, TTP

Question 28

RBCS with spikes

Answer 28

Burr cells or echinocytes - Valve replacements, RBC trauma