Pharma Flashcards
Haloperidol is not an appropriate drug for management of (A) Acute mania (B) Amenorrhea-galactorrhea syndrome (C) Phencyclidine intoxication (D) Schizoaffective disorders (E) Tourette syndrome
B) Amenorrhea-galactorrhea syndrome
Which mood-stabilizing agent is most likely to decrease the thyroid function? A. Carbamazepine B. Valproic acid C. Lithium D. Chlorpromazine E. Risperidone
C. Lithium
Which of the following determines the speed of recovery from intravenous anesthetics used for induction?
A. Liver metabolism of the drug
B. Protein binding of the drug
C. Ionization of the drug
D. Renal excretion of the drug
E. Redistribution of the drug from sites in the CNS
E. Redistribution of the drug from sites in the CNS
The combination of ethanol and disulfiram results in nausea and hypotension as a result of the accumulation of (A) Pyruvate (B) Acetate (C) Methanol (D) NADH (E) Acetaldehyde
E) Acetaldehyde
A 45-year-old man was started on therapy for hypertension and developed a persistent, drycough. Which is most likely responsible for this side effect? A. Lisinopril B. Losartan C. Nifedipine D. Atenolol E. Amlodipine
Lisinopril
Botulinum toxin blocks the release of acetylcholine from cholinergic nerve terminals. Which is a possible effect of botulinum toxin?
A. Skeletal muscle paralysis
B. Improvement of previous neuromuscular disease
C. Increased salivation
D. Reduced heart rate
E. Bronchodilation
A. Skeletal muscle paralysis
Which physiological change occurs when the parasympathetic system is activated? A. Increase in heart rate B. Inhibition of lacrimation (tears) C. Dilation of the pupil (mydriasis) D. Increase in gastric motility E. Increase contrcactility of heart
D. Increase in gastric motility
Which is correct regarding activation of receptors on the effector organs in the ANS?
A. Acetylcholine activates muscarinic receptors.
B. Acetylcholine activates adrenergic receptors.
C. Epinephrine activates nicotinic receptors.
D. Norepinephrine activates muscarinic receptors.
E. Epinephrine blocks adrenergic receptors.
A. Acetylcholine activates muscarinic receptors.
An asthma patient was given a nonselective beta agonist to relieve bronchoconstriction. Which adverse effect would you expect in this patient?
A. Bradycardia
B. Tachycardia
C. Hypotension (reduction in blood pressure)
D. Worsening bronchoconstriction
E. Cough
B. Tachycardia
If a fibrinolytic drug is used for treatment of acute myocardial infarction or pulmonary embolism, which of the following adverse drug effects is most likely to occur?
A. Hemorrhagic stroke
B. Development of antiplatelet antibodies
C. Encephalitis secondary to liver dysfunction
D. Acute renal failure
E. Neutropenia
Hemorrhagic stroke
While playing in the garden, a 7-year-old boy is stung by 3 bees. Because he has a previous history of bee sting allergy, he is brought to the emergency department by his mother who is very concerned about a possible anaphylactic reaction.
Following 2 questions;
Which of the following are probable signs of an anaphylactic reaction to bee stings?
A. Bronchodilation, tachycardia, hypertension, vomiting, diarrhea
B. Bronchospasm, tachycardia, hypotension, laryngeal edema
C. Diarrhea, bradycardia, vomiting
D. Laryngeal edema, bradycardia, hypotension, diarrhea
E. Miosis, tachycardia, vomiting, diarrhea
Bronchospasm, tachycardia, hypotension, laryngeal edema
If this child has signs of anaphylaxis, what is the main treatment of choice? A. Diphenhydramine (an antihistamine) B. Epinephrine C. Ephedrine D. Isoproterenol E. Methylprednisolone (a corticosteroid)
Epinephrine
Which of the followings are the drugs of choice in emergency department management of acute asthma attack (crisis, exacerbation) in adults ?
A. Oxygen, Salbutamol, Ipratroprium, Methylprednisolone
B. Oxygen, Salmeterol, Atropine, Cromolyn
C. Epinephrine, Theophylline, Zileuton, Prednisone
D. Oxygen, Omalizumab, Montelukast, Tiotropium
E. Salbutamol, Ipratrorium, Aminophylline, Beclamethasone
Oxygen, Salbutamol, Ipratroprium, Methylprednisolone
Genetic polymorphisms in certain hepatic enzymes involved in drug metabolism are established to be responsible for variations in analgesic response to A. Buprenorphine B. Codeine C. Fentanyl D. Methadone E. Tramadol
Codeine
Which of the following is an analgesic and antipyretic drug that lacks an anti-inflammatory action? A. Probenecid B. Celecoxib C. Colchicine D. Indomethacin E Acetaminophen
Acetaminophen
Postoperative vomiting is uncommon with this intravenous agent, and patients are often able to ambulate sooner than those who receive other anesthetics. (A) Enflurane (B) Etomidate (C) Midazolam (D) Propofol (E) Thiopental
Propofol
With chronic use in seizure states, the adverse effects of this drug include coarsening of facial features, hirsutism, and gingival hyperplasia. (A) Carbamazepine (B) Ethosuximide (C) Zonisamide (D) Tiagabine (E) Phenytoin
Phenytoin